Increased sensitivity to triiodothyronine (T3) of broiler lines with a high susceptibility for ascites.

E. Decuypere, C. Vega, T. Bartha, J. Buyse, J. Zoons, G. A. Albers

Research output: Contribution to journalArticle

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Abstract

1. In the studies reported here, broiler lines divergently selected for susceptibility to ascites under low temperature conditions were tested for their sensitivity to 3,3',5-triiodothyronine (T3) with respect to growth rate, rate of mortality, plasma concentrations of T3, right ventricular hypertrophy (RVH) and incidence of ascites. 2. Mean body weight of the ascites-susceptible line (BC-line) was higher than that of the ascites-resistant line (A-line). Adding 0.5 mg T3/kg of the diet depressed growth rate to the same extent in both lines. The effect of T3 on growth was more pronounced for males than for females. 3. T3-supplementation increased the relative weight of the heart and the incidence of RVH to the same extent in both lines. More of the T3-treated BC-line chickens had fluid accumulation in the abdominal cavity than the T3-treated A-line chickens. 4. Dietary T3-treatment depressed the plasma concentration of growth hormone (GH) profoundly and insulin-like growth factor (IGF-I) slightly but to the same extent in both lines. The coefficient of variation of GH concentrations indicate that T3 treatment mainly decreased GH-pulsatility in young growing broilers. 5. Higher doses of dietary T3 (1 and 2 mg/kg) increased mortality in a dose-dependent manner. With 2 mg T3/kg, mortality in the BC-line was almost double that in the A-line. 6. These studies indicate that the development of ascites could be linked with thyroid function. Moreover, dietary T3 supplementation could be used to help identify ascites-inducing factors or genetic lines with differential sensitivity for ascites.

Original languageEnglish
Pages (from-to)287-297
Number of pages11
JournalBritish Poultry Science
Volume35
Issue number2
Publication statusPublished - May 1994

Fingerprint

ascites
Triiodothyronine
triiodothyronine
Ascites
broiler chickens
Growth Hormone
Right Ventricular Hypertrophy
Insulin-Like Growth Factor I
somatotropin
Mortality
Chickens
Growth
Reverse Triiodothyronine
hypertrophy
Abdominal Cavity
Incidence
Dietary Supplements
chickens
incidence
thyroid function

ASJC Scopus subject areas

  • Animal Science and Zoology

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Increased sensitivity to triiodothyronine (T3) of broiler lines with a high susceptibility for ascites. / Decuypere, E.; Vega, C.; Bartha, T.; Buyse, J.; Zoons, J.; Albers, G. A.

In: British Poultry Science, Vol. 35, No. 2, 05.1994, p. 287-297.

Research output: Contribution to journalArticle

Decuypere, E, Vega, C, Bartha, T, Buyse, J, Zoons, J & Albers, GA 1994, 'Increased sensitivity to triiodothyronine (T3) of broiler lines with a high susceptibility for ascites.', British Poultry Science, vol. 35, no. 2, pp. 287-297.
Decuypere, E. ; Vega, C. ; Bartha, T. ; Buyse, J. ; Zoons, J. ; Albers, G. A. / Increased sensitivity to triiodothyronine (T3) of broiler lines with a high susceptibility for ascites. In: British Poultry Science. 1994 ; Vol. 35, No. 2. pp. 287-297.
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