Increased prevalence of factor V Leiden mutation in premature but not in full-term infants with grade I intracranial haemorrhage

K. Komlósi, V. Havasi, J. Bene, J. Storcz, J. Stankovics, G. Mohay, J. Weisenbach, G. Kosztolányi, B. Melegh

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Objectives: In the current prospective study our aim was to analyse the distribution of the factor V Leiden (G1691A) mutation in preterm and full-term neonates with grade I intraventricular haemorrhage and in control neonates. Study Method: A group of 125 individually selected neonates with grade I intraventricular haemorrhage and 128 controls were investigated. Results: The allele frequency was 7.2% in the total population of affected infants while it was 3.9% in the controls (p <0.05); the latter corresponds to an average European allele frequency in healthy populations. When the infants were grouped as premature (

Original languageEnglish
Pages (from-to)56-59
Number of pages4
JournalBiology of the Neonate
Volume87
Issue number1
DOIs
Publication statusPublished - 2005

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Intracranial Hemorrhages
Newborn Infant
Gene Frequency
Mutation
Hemorrhage
Population
Prospective Studies
factor V Leiden

Keywords

  • Factor V Leiden
  • Grade I IVH
  • Preterm neonates
  • Prothrombotic mutations

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

Cite this

Increased prevalence of factor V Leiden mutation in premature but not in full-term infants with grade I intracranial haemorrhage. / Komlósi, K.; Havasi, V.; Bene, J.; Storcz, J.; Stankovics, J.; Mohay, G.; Weisenbach, J.; Kosztolányi, G.; Melegh, B.

In: Biology of the Neonate, Vol. 87, No. 1, 2005, p. 56-59.

Research output: Contribution to journalArticle

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AU - Bene, J.

AU - Storcz, J.

AU - Stankovics, J.

AU - Mohay, G.

AU - Weisenbach, J.

AU - Kosztolányi, G.

AU - Melegh, B.

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