Increased Lipocalin 2 level may have important role in thrombotic events in patients with polycythemia vera and essential thrombocythemia

P. Rajnics, Kellner, Karádi, M. Moizs, Cs Bödör, P. A. Király, D. Marosvári, H. Andrikovics, M. Egyed

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The aim of our study was to evaluate the possible effect of lipocalin 2 on thrombotic events in polycythemia vera and essential thrombocythemia patients.The samples of 89 patients were collected and RNA based method was used to evaluate the relative gene expression level of lipocalin 2.74 samples were available for evaluation. Drawing a cut off point at level 30 relative expression rate, 13 patients with elevated lipocalin 2 expression had thrombotic events during the course of their disease.Based on these data high lipocalin 2 expression level seems to have strong positive predictive value on thrombotic events in patients with polycythemia vera and essential thrombocythemia. Lipocalin 2 may be useful in thrombotic risk stratification in these patients.

Original languageEnglish
JournalLeukemia Research
DOIs
Publication statusAccepted/In press - Jan 11 2016

Fingerprint

Essential Thrombocythemia
Polycythemia Vera
Lipocalins
Lipocalin-2
RNA
Gene Expression

Keywords

  • Essential thrombocythemia
  • Lipocalin 2
  • Polycythemia vera
  • Thrombosis

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology

Cite this

Increased Lipocalin 2 level may have important role in thrombotic events in patients with polycythemia vera and essential thrombocythemia. / Rajnics, P.; Kellner; Karádi; Moizs, M.; Bödör, Cs; Király, P. A.; Marosvári, D.; Andrikovics, H.; Egyed, M.

In: Leukemia Research, 11.01.2016.

Research output: Contribution to journalArticle

Rajnics, P. ; Kellner ; Karádi ; Moizs, M. ; Bödör, Cs ; Király, P. A. ; Marosvári, D. ; Andrikovics, H. ; Egyed, M. / Increased Lipocalin 2 level may have important role in thrombotic events in patients with polycythemia vera and essential thrombocythemia. In: Leukemia Research. 2016.
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AU - Bödör, Cs

AU - Király, P. A.

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