Incorporating activity of ribosomes and integrity of ribosomal RNA

Piroska Hüvös, L. Vereczkey, Ö Gaál

Research output: Contribution to journalArticle

8 Citations (Scopus)


The interrelationship between the amino acid incorporating ability and the state of ribosomal-RNA in ribonuclease treated rat liver ribosomes was studied. It was shown that ribosomes containing no or only negligible amounts of 28 S ribosomal-RNA retained at least 30 per cent of their original incorporating activity /measured without addition of any exogenous messenger-RNA/. On the basis of these results we conclude that the integrity of the 28 S ribosomal-RNA molecule is not required for ribosomal function.

Original languageEnglish
Pages (from-to)1020-1026
Number of pages7
JournalBiochemical and biophysical research communications
Issue number4
Publication statusPublished - Nov 25 1970

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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