The interrelationship between the amino acid incorporating ability and the state of ribosomal-RNA in ribonuclease treated rat liver ribosomes was studied. It was shown that ribosomes containing no or only negligible amounts of 28 S ribosomal-RNA retained at least 30 per cent of their original incorporating activity /measured without addition of any exogenous messenger-RNA/. On the basis of these results we conclude that the integrity of the 28 S ribosomal-RNA molecule is not required for ribosomal function.
|Number of pages||7|
|Journal||Biochemical and biophysical research communications|
|Publication status||Published - Nov 25 1970|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology