Inclusion body hepatitis associated with fowl adenovirus type 8b in broiler flock in Slovenia - A case report

Marko Zadravec, Brigita Slavec, Uroš Krapež, Gyozo L. Kaján, Jožko Račnik, Polona Juntes, Rahela Juršič Cizerl, M. Benkó, Olga Zorman Rojs

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Inclusion body hepatitis (IBH) is an acute disease in chickens caused by fowl adenoviruses (FAdVs). Among twelve known FAdV types (FAdV-1 to 8a, and FAdV-8b to 11), classified into five different species (A-E), all of them were already involved in naturally occurring cases. The disease is mainly distributed in areas with intensive poultry industry. In Slovenia the etiological agent of IBH has not been confirmed to date. An outbreak of acute mortality affected a broiler flock of 12,000 animals. In two waves of elevated mortality rate, a total of 264 (2.2%) chickens were found dead in one week time. Affected birds showed ruffled feathers, depression, watery droppings and some of them limping. The most common pathological lesions seen on necropsy were pale, swollen and friable livers with subcapsular hemorrhages. On histological examination, acute hepatitis characterized by necrosis and hepatocytes, with large basophilic intranuclear inclusion bodies, were observed. The histological results were characteristic for IBH caused by adenovirus infection. The causative agent was identified as fowl adenovirus (FAdV) type 8b, a member of the Fowl adenovirus E species, based on PCR results of partial sequence of adenoviral polymerase and hexon gene. The confirmed type in our case is one of the most common causative agents involved in IBH. In addition, infectious bursal disease virus and infectious bronchitis virus were detected in the same flock.

Original languageEnglish
Pages (from-to)107-113
Number of pages7
JournalSlovenian Veterinary Research
Volume48
Issue number3-4
Publication statusPublished - 2011

Fingerprint

Slovenia
Inclusion Bodies
inclusion bodies
hepatitis
Adenoviridae
Hepatitis
flocks
broiler chickens
Fowl adenovirus E
chickens
case studies
Fowl adenovirus A
Chickens
nuclear inclusions
Infectious bursal disease virus
Infectious bronchitis virus
Adenoviridae Infections
Intranuclear Inclusion Bodies
acute course
Mortality

Keywords

  • Broilers
  • Fowl adenovirus 8b
  • Inclusion body hepatitis outbreak
  • Slovenia

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Zadravec, M., Slavec, B., Krapež, U., Kaján, G. L., Račnik, J., Juntes, P., ... Rojs, O. Z. (2011). Inclusion body hepatitis associated with fowl adenovirus type 8b in broiler flock in Slovenia - A case report. Slovenian Veterinary Research, 48(3-4), 107-113.

Inclusion body hepatitis associated with fowl adenovirus type 8b in broiler flock in Slovenia - A case report. / Zadravec, Marko; Slavec, Brigita; Krapež, Uroš; Kaján, Gyozo L.; Račnik, Jožko; Juntes, Polona; Cizerl, Rahela Juršič; Benkó, M.; Rojs, Olga Zorman.

In: Slovenian Veterinary Research, Vol. 48, No. 3-4, 2011, p. 107-113.

Research output: Contribution to journalArticle

Zadravec, M, Slavec, B, Krapež, U, Kaján, GL, Račnik, J, Juntes, P, Cizerl, RJ, Benkó, M & Rojs, OZ 2011, 'Inclusion body hepatitis associated with fowl adenovirus type 8b in broiler flock in Slovenia - A case report', Slovenian Veterinary Research, vol. 48, no. 3-4, pp. 107-113.
Zadravec M, Slavec B, Krapež U, Kaján GL, Račnik J, Juntes P et al. Inclusion body hepatitis associated with fowl adenovirus type 8b in broiler flock in Slovenia - A case report. Slovenian Veterinary Research. 2011;48(3-4):107-113.
Zadravec, Marko ; Slavec, Brigita ; Krapež, Uroš ; Kaján, Gyozo L. ; Račnik, Jožko ; Juntes, Polona ; Cizerl, Rahela Juršič ; Benkó, M. ; Rojs, Olga Zorman. / Inclusion body hepatitis associated with fowl adenovirus type 8b in broiler flock in Slovenia - A case report. In: Slovenian Veterinary Research. 2011 ; Vol. 48, No. 3-4. pp. 107-113.
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