Incidence, antibiotic resistance and clonal relations of MRSA strains isolated from a Romanian university hospital

Edit Székely, Lilla Lörinczi, Doina Bilca, Eleonóra Fodor, J. Sóki, Monica Sabau

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Our aim was to estimate the frequency and characteristics of methicillin-resistant Staphylococcus aureus (MRSA) strains occurring in a Romanian teaching hospital. We retrospectively studied isolates from infected or colonized patients treated at the intensive care and surgical units during January 2004-December 2005. The antibiotic susceptibility of MRSA strains and the presence of mecA gene were determined. Consecutively occurring strains isolated through a three-month period were typed using pulsed field gel electrophoresis. A total of 423 S. aureus strains were identified, methicillin-resistance was detected in 211 (49.9%) strains. Most of them were multiresistant. One of the MRSA genotypes identified by PFGE was commonly recovered from patients treated in the intensive care unit. According to our results. MRSA strains were frequently isolated pathogens in our hospital and there is an urgent need to enhance infection control efforts.

Original languageEnglish
Pages (from-to)1-13
Number of pages13
JournalActa Microbiologica et Immunologica Hungarica
Volume55
Issue number1
DOIs
Publication statusPublished - Mar 2008

Fingerprint

Methicillin-Resistant Staphylococcus aureus
Microbial Drug Resistance
Incidence
Intensive Care Units
Methicillin Resistance
Pulsed Field Gel Electrophoresis
Infection Control
Teaching Hospitals
Staphylococcus aureus
Genotype
Anti-Bacterial Agents
Genes

Keywords

  • Methicillin-resistant Staphylococcus aureus
  • Nosocomial infection

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Medicine(all)
  • Microbiology

Cite this

Incidence, antibiotic resistance and clonal relations of MRSA strains isolated from a Romanian university hospital. / Székely, Edit; Lörinczi, Lilla; Bilca, Doina; Fodor, Eleonóra; Sóki, J.; Sabau, Monica.

In: Acta Microbiologica et Immunologica Hungarica, Vol. 55, No. 1, 03.2008, p. 1-13.

Research output: Contribution to journalArticle

Székely, Edit ; Lörinczi, Lilla ; Bilca, Doina ; Fodor, Eleonóra ; Sóki, J. ; Sabau, Monica. / Incidence, antibiotic resistance and clonal relations of MRSA strains isolated from a Romanian university hospital. In: Acta Microbiologica et Immunologica Hungarica. 2008 ; Vol. 55, No. 1. pp. 1-13.
@article{7a5e61f4aa974f4bbe8107fd5389fd3f,
title = "Incidence, antibiotic resistance and clonal relations of MRSA strains isolated from a Romanian university hospital",
abstract = "Our aim was to estimate the frequency and characteristics of methicillin-resistant Staphylococcus aureus (MRSA) strains occurring in a Romanian teaching hospital. We retrospectively studied isolates from infected or colonized patients treated at the intensive care and surgical units during January 2004-December 2005. The antibiotic susceptibility of MRSA strains and the presence of mecA gene were determined. Consecutively occurring strains isolated through a three-month period were typed using pulsed field gel electrophoresis. A total of 423 S. aureus strains were identified, methicillin-resistance was detected in 211 (49.9{\%}) strains. Most of them were multiresistant. One of the MRSA genotypes identified by PFGE was commonly recovered from patients treated in the intensive care unit. According to our results. MRSA strains were frequently isolated pathogens in our hospital and there is an urgent need to enhance infection control efforts.",
keywords = "Methicillin-resistant Staphylococcus aureus, Nosocomial infection",
author = "Edit Sz{\'e}kely and Lilla L{\"o}rinczi and Doina Bilca and Eleon{\'o}ra Fodor and J. S{\'o}ki and Monica Sabau",
year = "2008",
month = "3",
doi = "10.1556/AMicr.55.2008.1.1",
language = "English",
volume = "55",
pages = "1--13",
journal = "Acta Microbiologica et Immunologica Hungarica",
issn = "1217-8950",
publisher = "Akademiai Kiado",
number = "1",

}

TY - JOUR

T1 - Incidence, antibiotic resistance and clonal relations of MRSA strains isolated from a Romanian university hospital

AU - Székely, Edit

AU - Lörinczi, Lilla

AU - Bilca, Doina

AU - Fodor, Eleonóra

AU - Sóki, J.

AU - Sabau, Monica

PY - 2008/3

Y1 - 2008/3

N2 - Our aim was to estimate the frequency and characteristics of methicillin-resistant Staphylococcus aureus (MRSA) strains occurring in a Romanian teaching hospital. We retrospectively studied isolates from infected or colonized patients treated at the intensive care and surgical units during January 2004-December 2005. The antibiotic susceptibility of MRSA strains and the presence of mecA gene were determined. Consecutively occurring strains isolated through a three-month period were typed using pulsed field gel electrophoresis. A total of 423 S. aureus strains were identified, methicillin-resistance was detected in 211 (49.9%) strains. Most of them were multiresistant. One of the MRSA genotypes identified by PFGE was commonly recovered from patients treated in the intensive care unit. According to our results. MRSA strains were frequently isolated pathogens in our hospital and there is an urgent need to enhance infection control efforts.

AB - Our aim was to estimate the frequency and characteristics of methicillin-resistant Staphylococcus aureus (MRSA) strains occurring in a Romanian teaching hospital. We retrospectively studied isolates from infected or colonized patients treated at the intensive care and surgical units during January 2004-December 2005. The antibiotic susceptibility of MRSA strains and the presence of mecA gene were determined. Consecutively occurring strains isolated through a three-month period were typed using pulsed field gel electrophoresis. A total of 423 S. aureus strains were identified, methicillin-resistance was detected in 211 (49.9%) strains. Most of them were multiresistant. One of the MRSA genotypes identified by PFGE was commonly recovered from patients treated in the intensive care unit. According to our results. MRSA strains were frequently isolated pathogens in our hospital and there is an urgent need to enhance infection control efforts.

KW - Methicillin-resistant Staphylococcus aureus

KW - Nosocomial infection

UR - http://www.scopus.com/inward/record.url?scp=42149136323&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=42149136323&partnerID=8YFLogxK

U2 - 10.1556/AMicr.55.2008.1.1

DO - 10.1556/AMicr.55.2008.1.1

M3 - Article

C2 - 18507148

AN - SCOPUS:42149136323

VL - 55

SP - 1

EP - 13

JO - Acta Microbiologica et Immunologica Hungarica

JF - Acta Microbiologica et Immunologica Hungarica

SN - 1217-8950

IS - 1

ER -