Hullámok nyelvén: a szerotonin és az alvási oszcillációk.

Translated title of the contribution: In waves' parlance: serotonin and sleep oscillations

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

The close and complex relationship between serotonin and sleep-waking states has special theoretical and practical importance. There are available scientific data regarding this issue, but the apparently contradictory and insufficiently clarified nature of the problem halts up the systematization and exploitation of this knowledge. While reviewing the role of serotonin in sleep regulation a special attention to the differentiation between the immediate arousing and the slowly developing circadian phase resetting and sleep homeostatic functions of serotonin is paid. As regarding the differentiation of receptor subtypes the article focuses on circadian rhythm and REM regulatory/modulatory functions in relation with 5-HT1A/7 and 5-HT3 receptors, as well as on sleep homeostasis, sleep intensity, ultradian sleep organization, and sleep continuity in relation with 5-HT2A receptors. Moreover, there is suggestive data for the reciprocal interactions between serotonin, neural plasticity and sleep spindling, which might provide new insights to the neuropsychopharmacological characterization of the mechanisms of action and effects of drugs acting through the serotonergic system.

Translated title of the contributionIn waves' parlance: serotonin and sleep oscillations
Original languageHungarian
Pages (from-to)191-199
Number of pages9
JournalNeuropsychopharmacologia Hungarica : a Magyar Pszichofarmakológiai Egyesület lapja = official journal of the Hungarian Association of Psychopharmacology
Volume11
Issue number3
Publication statusPublished - Sep 2009

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Clinical Neurology

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