In vitro study of elements in herbal remedies

K. Szentmihályi, M. Hajdú, J. Fodor, L. Kótai, A. Blázovics, A. Somogyi, M. Then

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Decreased glucose tolerance is a first sign of diabetes mellitus and therefore rigorous control must be taken in carbohydrate and lipid metabolisms. Herbal remedies (lyophilized extracts of Myrtilli folium and Phaseoli fructus sine seminibus (L1), Myrtilli folium, Phaseoli fructus sine seminibus, and Salviae folium (L2) are traditionally used in mid-European folk medicine and in common adjuvant therapy for the prevention of complications in type 2 diabetes. Significant iron (355.7 ± 13.8 mg/kg) and zinc (84.73 ± 1.83 mg/kg) concentration was found in L1 and chromium (3.82 ± 2.71 mg/kg) in L2. Ion concentrations in teas made from L1 and L2 are relatively low because the quantities of metal ions in teas do not cover the daily need, although the teas are good sources for some elements. According to the Recommended Daily Allowances, the tea of L1 is a good source for iron and manganese, whereas for chromium, the tea of L2 is better. For evaluating the element bioavailability, an in vitro dialysis system was applied to determine the element transfer from tea of the lyophilized sample to the plasma (buffer pH=7.4). Measurements showed that the elements transferred between 6.90% (iron from tea of L2) and 90.05% (chromium from tea of L2) through the membrane from teas to the plasma. Metal ions in teas of herbal remedies might contribute to the favorable therapeutic effect of preventing complications, because they might transfer through the membranes in relatively high percentages.

Original languageEnglish
Pages (from-to)143-150
Number of pages8
JournalBiological Trace Element Research
Volume114
Issue number1-3
DOIs
Publication statusPublished - 2006

Fingerprint

Tea
Chromium
Iron
Ions
Medical problems
Metal ions
Metals
In Vitro Techniques
Recommended Dietary Allowances
Membranes
Plasmas
Carbohydrate Metabolism
Traditional Medicine
Therapeutic Uses
Dialysis
Manganese
Lipid Metabolism
Type 2 Diabetes Mellitus
Biological Availability
Zinc

Keywords

  • Elements
  • In vitro transfer
  • Medicinal plant teas

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

In vitro study of elements in herbal remedies. / Szentmihályi, K.; Hajdú, M.; Fodor, J.; Kótai, L.; Blázovics, A.; Somogyi, A.; Then, M.

In: Biological Trace Element Research, Vol. 114, No. 1-3, 2006, p. 143-150.

Research output: Contribution to journalArticle

@article{7e442f84877e4b228f8bda1006eb1481,
title = "In vitro study of elements in herbal remedies",
abstract = "Decreased glucose tolerance is a first sign of diabetes mellitus and therefore rigorous control must be taken in carbohydrate and lipid metabolisms. Herbal remedies (lyophilized extracts of Myrtilli folium and Phaseoli fructus sine seminibus (L1), Myrtilli folium, Phaseoli fructus sine seminibus, and Salviae folium (L2) are traditionally used in mid-European folk medicine and in common adjuvant therapy for the prevention of complications in type 2 diabetes. Significant iron (355.7 ± 13.8 mg/kg) and zinc (84.73 ± 1.83 mg/kg) concentration was found in L1 and chromium (3.82 ± 2.71 mg/kg) in L2. Ion concentrations in teas made from L1 and L2 are relatively low because the quantities of metal ions in teas do not cover the daily need, although the teas are good sources for some elements. According to the Recommended Daily Allowances, the tea of L1 is a good source for iron and manganese, whereas for chromium, the tea of L2 is better. For evaluating the element bioavailability, an in vitro dialysis system was applied to determine the element transfer from tea of the lyophilized sample to the plasma (buffer pH=7.4). Measurements showed that the elements transferred between 6.90{\%} (iron from tea of L2) and 90.05{\%} (chromium from tea of L2) through the membrane from teas to the plasma. Metal ions in teas of herbal remedies might contribute to the favorable therapeutic effect of preventing complications, because they might transfer through the membranes in relatively high percentages.",
keywords = "Elements, In vitro transfer, Medicinal plant teas",
author = "K. Szentmih{\'a}lyi and M. Hajd{\'u} and J. Fodor and L. K{\'o}tai and A. Bl{\'a}zovics and A. Somogyi and M. Then",
year = "2006",
doi = "10.1385/BTER:114:1:143",
language = "English",
volume = "114",
pages = "143--150",
journal = "Biological Trace Element Research",
issn = "0163-4984",
publisher = "Humana Press",
number = "1-3",

}

TY - JOUR

T1 - In vitro study of elements in herbal remedies

AU - Szentmihályi, K.

AU - Hajdú, M.

AU - Fodor, J.

AU - Kótai, L.

AU - Blázovics, A.

AU - Somogyi, A.

AU - Then, M.

PY - 2006

Y1 - 2006

N2 - Decreased glucose tolerance is a first sign of diabetes mellitus and therefore rigorous control must be taken in carbohydrate and lipid metabolisms. Herbal remedies (lyophilized extracts of Myrtilli folium and Phaseoli fructus sine seminibus (L1), Myrtilli folium, Phaseoli fructus sine seminibus, and Salviae folium (L2) are traditionally used in mid-European folk medicine and in common adjuvant therapy for the prevention of complications in type 2 diabetes. Significant iron (355.7 ± 13.8 mg/kg) and zinc (84.73 ± 1.83 mg/kg) concentration was found in L1 and chromium (3.82 ± 2.71 mg/kg) in L2. Ion concentrations in teas made from L1 and L2 are relatively low because the quantities of metal ions in teas do not cover the daily need, although the teas are good sources for some elements. According to the Recommended Daily Allowances, the tea of L1 is a good source for iron and manganese, whereas for chromium, the tea of L2 is better. For evaluating the element bioavailability, an in vitro dialysis system was applied to determine the element transfer from tea of the lyophilized sample to the plasma (buffer pH=7.4). Measurements showed that the elements transferred between 6.90% (iron from tea of L2) and 90.05% (chromium from tea of L2) through the membrane from teas to the plasma. Metal ions in teas of herbal remedies might contribute to the favorable therapeutic effect of preventing complications, because they might transfer through the membranes in relatively high percentages.

AB - Decreased glucose tolerance is a first sign of diabetes mellitus and therefore rigorous control must be taken in carbohydrate and lipid metabolisms. Herbal remedies (lyophilized extracts of Myrtilli folium and Phaseoli fructus sine seminibus (L1), Myrtilli folium, Phaseoli fructus sine seminibus, and Salviae folium (L2) are traditionally used in mid-European folk medicine and in common adjuvant therapy for the prevention of complications in type 2 diabetes. Significant iron (355.7 ± 13.8 mg/kg) and zinc (84.73 ± 1.83 mg/kg) concentration was found in L1 and chromium (3.82 ± 2.71 mg/kg) in L2. Ion concentrations in teas made from L1 and L2 are relatively low because the quantities of metal ions in teas do not cover the daily need, although the teas are good sources for some elements. According to the Recommended Daily Allowances, the tea of L1 is a good source for iron and manganese, whereas for chromium, the tea of L2 is better. For evaluating the element bioavailability, an in vitro dialysis system was applied to determine the element transfer from tea of the lyophilized sample to the plasma (buffer pH=7.4). Measurements showed that the elements transferred between 6.90% (iron from tea of L2) and 90.05% (chromium from tea of L2) through the membrane from teas to the plasma. Metal ions in teas of herbal remedies might contribute to the favorable therapeutic effect of preventing complications, because they might transfer through the membranes in relatively high percentages.

KW - Elements

KW - In vitro transfer

KW - Medicinal plant teas

UR - http://www.scopus.com/inward/record.url?scp=33846223306&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846223306&partnerID=8YFLogxK

U2 - 10.1385/BTER:114:1:143

DO - 10.1385/BTER:114:1:143

M3 - Article

C2 - 17205997

AN - SCOPUS:33846223306

VL - 114

SP - 143

EP - 150

JO - Biological Trace Element Research

JF - Biological Trace Element Research

SN - 0163-4984

IS - 1-3

ER -