In vitro study of Candida tropicalis isolates exhibiting paradoxical growth in the presence of high concentrations of caspofungin

G. Sóczó, G. Kardos, I. Varga, B. Kelentey, R. Gesztelyi, L. Majoros

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Paradoxical growth was noted in RPMI 1640 and antibiotic medium 3 in the case of 14 and 1 of 15 Candida tropicalis strains, respectively, at a caspofungin concentration of 12.5 μg/ml using minimum fungicidal concentration tests. Time-kill assays showed that against isolates killed at lower concentrations, caspofungin at a concentration of 12.5 μg/ml was only fungistatic.

Original languageEnglish
Pages (from-to)4474-4476
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume51
Issue number12
DOIs
Publication statusPublished - Dec 2007

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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