ABC transzporterek - Különös tekintettel az ABCG2-re - és gyógyszerjelölt molekulák kölcsö nhatásának predikciójára alkalmas in vitro módszerek

Translated title of the contribution: In vitro methods suitable for the prediction of drug and ABC transporter, especially ABCG2 interactions

Pál Ákos, Kis Emese, Méhn Dóra, Glavinas Hristos, Nagy Tünde, Mészáros Péter, Báthori György, Krajcsi Péter, Falkay György

Research output: Contribution to journalArticle

Abstract

ABCG2, a transporter of the ATP-binding cassette family, is known to play a prominent role in the absorption, distribution, metabolism, and excretion of xenobiotics. Drug-transporter interactions are commonly screened by in vitro systems using transfected insect and/or human cell lines.

Translated title of the contributionIn vitro methods suitable for the prediction of drug and ABC transporter, especially ABCG2 interactions
Original languageHungarian
Pages (from-to)205-216
Number of pages12
JournalActa pharmaceutica Hungarica
Volume77
Issue number4
Publication statusPublished - Dec 1 2007

ASJC Scopus subject areas

  • Pharmaceutical Science

Fingerprint Dive into the research topics of 'In vitro methods suitable for the prediction of drug and ABC transporter, especially ABCG2 interactions'. Together they form a unique fingerprint.

  • Cite this