ABC transzporterek - Különös tekintettel az ABCG2-re - és gyógyszerjelölt molekulák kölcsö nhatásának predikciójára alkalmas in vitro módszerek

Translated title of the contribution: In vitro methods suitable for the prediction of drug and ABC transporter, especially ABCG2 interactions

Pál Ákos, Kis Emese, Méhn Dóra, Glavinas Hristos, Nagy Tünde, Mészáros Péter, G. Báthori, Krajcsi Péter, G. Falkay

Research output: Contribution to journalArticle

Abstract

ABCG2, a transporter of the ATP-binding cassette family, is known to play a prominent role in the absorption, distribution, metabolism, and excretion of xenobiotics. Drug-transporter interactions are commonly screened by in vitro systems using transfected insect and/or human cell lines.

Original languageHungarian
Pages (from-to)205-216
Number of pages12
JournalActa Pharmaceutica Hungarica
Volume77
Issue number4
Publication statusPublished - 2007

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ATP-Binding Cassette Transporters
Xenobiotics
Drug Interactions
Insects
Adenosine Triphosphate
Cell Line
Pharmaceutical Preparations
ATP Binding Cassette Transporter, Sub-Family G, Member 2
In Vitro Techniques

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

ABC transzporterek - Különös tekintettel az ABCG2-re - és gyógyszerjelölt molekulák kölcsö nhatásának predikciójára alkalmas in vitro módszerek. / Ákos, Pál; Emese, Kis; Dóra, Méhn; Hristos, Glavinas; Tünde, Nagy; Péter, Mészáros; Báthori, G.; Péter, Krajcsi; Falkay, G.

In: Acta Pharmaceutica Hungarica, Vol. 77, No. 4, 2007, p. 205-216.

Research output: Contribution to journalArticle

Ákos, Pál ; Emese, Kis ; Dóra, Méhn ; Hristos, Glavinas ; Tünde, Nagy ; Péter, Mészáros ; Báthori, G. ; Péter, Krajcsi ; Falkay, G. / ABC transzporterek - Különös tekintettel az ABCG2-re - és gyógyszerjelölt molekulák kölcsö nhatásának predikciójára alkalmas in vitro módszerek. In: Acta Pharmaceutica Hungarica. 2007 ; Vol. 77, No. 4. pp. 205-216.
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