ABCG2, a transporter of the ATP-binding cassette family, is known to play a prominent role in the absorption, distribution, metabolism, and excretion of xenobiotics. Drug-transporter interactions are commonly screened by in vitro systems using transfected insect and/or human cell lines.
|Translated title of the contribution||In vitro methods suitable for the prediction of drug and ABC transporter, especially ABCG2 interactions|
|Number of pages||12|
|Journal||Acta pharmaceutica Hungarica|
|Publication status||Published - Dec 1 2007|
ASJC Scopus subject areas
- Pharmaceutical Science