In vitro melatonin secretion pattern of the avian pineal gland with special reference to light reactivity

M. Ghosh, V. Csernus, B. Mess

Research output: Contribution to journalArticle

6 Citations (Scopus)


Melatonin production of the chicken pineal gland was monitored in a long-term perifusion system. The spontaneous, circadian melatonin rhythm could not be influenced by keeping the pineal donor birds in constant light or constant dark environment for two weeks before sacrifice. Circadian melatonin rhythm developed even if the chickens were kept under continuous illumination from hatching to sacrifice, in 8 to 10 weeks of age. Constant illumination or continuous darkness, in vitro, does not extinguish only modifies the circadian melatonin rhythm (reduced amplitude). It was concluded that avian pineal has a genetically coded circadian rhythm which develops and is maintained without cyclic illumination and can only be slightly modulated by long-term changes in environmental lighting conditions.

Original languageEnglish
Pages (from-to)195-200
Number of pages6
JournalNeuroendocrinology Letters
Issue number3
Publication statusPublished - Jan 1 1994


ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Neurology
  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Psychiatry and Mental health

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