In vitro fertilizációs kezelések klinikánkon

Tíz év munkája a számok és eredmények tükrében (1994-2003)

Translated title of the contribution: In vitro fertilization at our department. A decade's work in figures and facts (1994-2003)

J. Urbancsek, Péter Fancsovits, Ákos Murber, Zsuzsa Tóthné-Gilán, Erik Hauzman, Z. Papp

Research output: Contribution to journalArticle

Abstract

We report here on the first decade of in vitro fertilization (IVF) treatments performed at a newly established clinical infertility and assisted reproductive unit. Objective: We present the number of treatment cycles, the distribution of treatment modalities ("classical" IVF and intracytoplasmic sperm injection, ICSI) and success rates, and relate them to national and international data. Methods: During the last decade, ICSI was introduced gradually and is now used routinely at our department. In certain cases of azoospermia, testicular sperm extraction (TESE) is used to retrieve male gametes for ICSI. Embryo cryopreservation, which is also part of the routine, provides the chance to establish pregnancy in subsequent cycles without the need to repeat hormonal stimulation. Preimplantation genetic diagnosis helps us to avoid transferring embryos carrying certain hereditary diseases. Results: 1517 IVF cycles were started in the past ten years. Oocyte pickup and IVF were performed in 1423 cases. In the end of the described period, ICSI was used in more than two thirds of treatment cycles. Pregnancy rates were 39.0% per embryo transfer (ET), 36.3% per oocyte pickup, and 34.0% per started cycle. Clinical pregnancy was achieved in 34.2% per ET, and the delivery rate was 27.9% per ET. These success rates have exceeded the national average every year since 1996. Pregnancy rates in frozen-thawed ET cycles and in cryo-TESE-ICSI cycles are in the range of international data. Conclusions: We attribute the gradual and continuous improvement in our success rates to rigorous and well-coordinated clinical and laboratory work and to judicious adoption of the latest assisted reproductive techniques.

Original languageHungarian
Pages (from-to)7-14
Number of pages8
JournalOrvosi Hetilap
Volume147
Issue number1
Publication statusPublished - Jan 8 2006

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Intracytoplasmic Sperm Injections
Fertilization in Vitro
Embryo Transfer
Pregnancy Rate
Oocytes
Spermatozoa
Embryonic Structures
Preimplantation Diagnosis
Pregnancy
Azoospermia
Assisted Reproductive Techniques
Inborn Genetic Diseases
Cryopreservation
Therapeutics
Germ Cells
Infertility

ASJC Scopus subject areas

  • Medicine(all)

Cite this

In vitro fertilizációs kezelések klinikánkon : Tíz év munkája a számok és eredmények tükrében (1994-2003). / Urbancsek, J.; Fancsovits, Péter; Murber, Ákos; Tóthné-Gilán, Zsuzsa; Hauzman, Erik; Papp, Z.

In: Orvosi Hetilap, Vol. 147, No. 1, 08.01.2006, p. 7-14.

Research output: Contribution to journalArticle

Urbancsek, J. ; Fancsovits, Péter ; Murber, Ákos ; Tóthné-Gilán, Zsuzsa ; Hauzman, Erik ; Papp, Z. / In vitro fertilizációs kezelések klinikánkon : Tíz év munkája a számok és eredmények tükrében (1994-2003). In: Orvosi Hetilap. 2006 ; Vol. 147, No. 1. pp. 7-14.
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