In vitro effect of transfer factor on the cyclic nucleotide level of human lymphocyte in chronic lymphocytic leukaemia and of mouse lymphocytes

L. Kalmar, K. Nékám, I. Láng, G. Kelemen, P. Gergely

Research output: Contribution to journalArticle

Abstract

In the present study transfer factor (TF) failed to produce any change in the cAMP- and cGMP-levels of lymphocytes of patients with chronic lymphoid leukemia. (CLL). This is attributed to the malignant transformation of the lymphocytes or to a changed proportion of different lymphocyte populations in CLL. Human TF leaves the cyclic nucleotide levels of splenic lymphocytes of BALB/c mice unaffected.

Original languageEnglish
Pages (from-to)43-46
Number of pages4
JournalActa Medica Academiae Scientiarum Hungaricae
Volume35
Issue number1
Publication statusPublished - 1978

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Transfer Factor
Cyclic Nucleotides
B-Cell Chronic Lymphocytic Leukemia
Lymphocytes
Lymphoid Leukemia
Lymphocyte Activation
Population
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "In the present study transfer factor (TF) failed to produce any change in the cAMP- and cGMP-levels of lymphocytes of patients with chronic lymphoid leukemia. (CLL). This is attributed to the malignant transformation of the lymphocytes or to a changed proportion of different lymphocyte populations in CLL. Human TF leaves the cyclic nucleotide levels of splenic lymphocytes of BALB/c mice unaffected.",
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AU - Kelemen, G.

AU - Gergely, P.

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