Improving accuracy in DOSY and diffusion measurements using triaxial field gradients

P. Király, Iain Swan, Mathias Nilsson, Gareth A. Morris

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

NMR measurements of diffusion in solution, whether primarily quantitative, or, (as in DOSY, Diffusion-Ordered Spectroscopy) qualitative, can be particularly demanding. Here we show how the use of appropriate transverse (x, y) pulsed field gradients, orthogonal to the more usual z axis pulsed field gradient applied along the long axis of the sample, can greatly reduce two important sources of systematic error in diffusion experiments. These are the extra signal attenuation caused by sample convection, and gradient-dependent signal phase shifts caused by the magnetic field and field-frequency lock disturbances generated by field gradient pulses.

Original languageEnglish
Pages (from-to)24-30
Number of pages7
JournalJournal of Magnetic Resonance
Volume270
DOIs
Publication statusPublished - Sep 1 2016

Fingerprint

gradients
Convection
Systematic errors
Magnetic Fields
Phase shift
Spectrum Analysis
Research Design
Nuclear magnetic resonance
systematic errors
Spectroscopy
Magnetic fields
convection
phase shift
disturbances
attenuation
nuclear magnetic resonance
pulses
Experiments
magnetic fields
spectroscopy

Keywords

  • Convection
  • Diffusion
  • DOSY
  • NMR
  • Triaxial gradient

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Biochemistry
  • Biophysics
  • Condensed Matter Physics

Cite this

Improving accuracy in DOSY and diffusion measurements using triaxial field gradients. / Király, P.; Swan, Iain; Nilsson, Mathias; Morris, Gareth A.

In: Journal of Magnetic Resonance, Vol. 270, 01.09.2016, p. 24-30.

Research output: Contribution to journalArticle

Király, P. ; Swan, Iain ; Nilsson, Mathias ; Morris, Gareth A. / Improving accuracy in DOSY and diffusion measurements using triaxial field gradients. In: Journal of Magnetic Resonance. 2016 ; Vol. 270. pp. 24-30.
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