Improvement of perinatal outcome in diabetic pregnant women.

A. Szilagyi, I. Szabó

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Obstetrical and perinatal outcomes in newborns of diabetic pregnant women depend on metabolic control and fetal surveillance during pregnancy. The effects of fetal surveillance on perinatal mortality and morbidity was analyzed in diabetic pregnant women with appropriate glucose control in our regional center for diabetes and pregnancy. 480 deliveries complicated by frank or gestational diabetes occurred in our Department in the period of 1988-1999. Perinatal mortality and morbidity, prevalence of premature deliveries, methods of fetal surveillance, options for respiratory distress syndrome (RDS) profilaxis, cesarean section rate, timing of delivery and its indications and occurrence of malformations have been analyzed. It was found that malformation rate and perinatal mortality may be reduced to even lower level than that of in healthy pregnant women by appropriate glucose control and by using the latest methods of intrauterine fetal surveillance including cardiotocography (non stress test and oxytocin challenge test), doppler fetal artery velocimetry and fetal pulse oximetry. Timing of delivery was needed in 35% of the cases with IDDM and 15% of gestational diabetes due to chronic placental insufficiency. If labour induction was needed before the 38 weeks, amniocentesis was performed to test fetal lung maturity. Direct fetal glucocorticoid administration was used to enhance fetal lung maturation in 14 cases. C-section rate was slightly higher than that of in non diabetic pregnant women. Our perinatal morbidity data (macrosomia, hyperbilirubinemia, hypoglycemia, injuries, infections) are comparable with the data from the literature. Although perinatal mortality with the help of thorough fetal surveillance is even better in diabetic pregnant women than in non diabetic patients, future eye should be focused on factors affecting perinatal morbidity, because it is still higher than in newborns of healthy mothers.

Original languageEnglish
Pages (from-to)55-56
Number of pages2
JournalEarly pregnancy (Online)
Volume5
Issue number1
Publication statusPublished - Jan 2001

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Perinatal Mortality
Pregnant Women
Morbidity
Gestational Diabetes
Newborn Infant
Cardiotocography
Placental Insufficiency
Induced Labor
Glucose
Pregnancy
Lung
Hyperbilirubinemia
Oximetry
Amniocentesis
Rheology
Oxytocin
Type 1 Diabetes Mellitus
Exercise Test
Hypoglycemia
Cesarean Section

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Improvement of perinatal outcome in diabetic pregnant women. / Szilagyi, A.; Szabó, I.

In: Early pregnancy (Online), Vol. 5, No. 1, 01.2001, p. 55-56.

Research output: Contribution to journalArticle

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