Improved synthesis of 2,2′-bipyrimidine

Gábor Vlád, István T. Horváth

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A high-yield synthesis was developed for the preparation of 2,2′-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4′,6,6′-tetramethyl-2,2′-bipyrimidine (2) and 5,5′-dibromo-2,2′-bipyrimidine (3).

Original languageEnglish
Pages (from-to)6550-6552
Number of pages3
JournalJournal of Organic Chemistry
Issue number18
Publication statusPublished - Sep 6 2002

ASJC Scopus subject areas

  • Organic Chemistry

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