One of major hazards of hormone replacement therapy /HRT/ is the endometrium carcinoma. Transvaginal sonography /TVS/ is a useful tool for screening endometrial abnormalities. During the last 18 months 165 TVS at postmenopause women undergoing HRT. Endometrium was considered abnormal when thickness of the endometrium, measured with TVS was equal to, or above 8 mm. All 11 women with the above findings underwent diagnostic curettage. No histological abnormality was found in 3 cases. Atrophy in 3, endometrial hyperplasia in 3 and atypical adenomatous hyperplasia in 2 cases were observed. In the two cases of adenomatous hyperplasia were performed hysterectomy. The postoperative hystology justified the previous findings in both cases. TVS is a suitable and necessary screening method for the evaluation of the endometrium during HRT.
|Pages (from-to)||OGP 6101|
|Journal||Ultrasound in Medicine and Biology|
|Issue number||Suppl 1|
|Publication status||Published - Jan 1 1997|
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Acoustics and Ultrasonics