Importance of screening endometrium thickness during hormone replacement therapy

Gabor Hetenyi, Gabor Lazar, Zoltan Ruttner, Pal Siklos, Laszlo Ungar

Research output: Contribution to journalArticle


One of major hazards of hormone replacement therapy /HRT/ is the endometrium carcinoma. Transvaginal sonography /TVS/ is a useful tool for screening endometrial abnormalities. During the last 18 months 165 TVS at postmenopause women undergoing HRT. Endometrium was considered abnormal when thickness of the endometrium, measured with TVS was equal to, or above 8 mm. All 11 women with the above findings underwent diagnostic curettage. No histological abnormality was found in 3 cases. Atrophy in 3, endometrial hyperplasia in 3 and atypical adenomatous hyperplasia in 2 cases were observed. In the two cases of adenomatous hyperplasia were performed hysterectomy. The postoperative hystology justified the previous findings in both cases. TVS is a suitable and necessary screening method for the evaluation of the endometrium during HRT.

Original languageEnglish
Pages (from-to)OGP 6101
JournalUltrasound in Medicine and Biology
Issue numberSuppl 1
Publication statusPublished - Jan 1 1997


ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

Cite this