Impact of neonatal imprinting with vitamin A or D on the hormone content of rat immune cells

G. Csaba, Peter Kovács, E. Pállinger

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Neonatal single vitamin A (retinol; 3 mg) or vitamin D3 (cholecalciferol; 0.05 mg) treatment (imprinting) was done in male and female rats and 2 months later the endorphin, triiodothyronine (T3) and ACTH content of immune cells (peritoneal lymphocytes, monocyte-granulocyte- macrophage group [mo-gran], mast cells and thymic lymphocytes) were studied immunocytochemically by using flow cytometry and confocal microscopy. The T 3 content was significantly decreased in peritoneal lymphocytes and in mo-gran and the endorphin content decreased in thymocytes of male animals, while ACTH was decreased in female lymphocytes and mo-gran. Vitamin D treatment was absolutely ineffective. The imprinting effects of vitamins A and D and their differences are discussed. The results call attention to the possible harmful effect of vitamin treatments during the perinatal critical period.

Original languageEnglish
Pages (from-to)717-721
Number of pages5
JournalCell Biochemistry and Function
Volume25
Issue number6
DOIs
Publication statusPublished - Nov 2007

Fingerprint

Lymphocytes
Vitamin A
Vitamin D
Rats
Macrophages
Granulocytes
Hormones
Endorphins
Monocytes
Cholecalciferol
Adrenocorticotropic Hormone
Flow cytometry
Confocal microscopy
Triiodothyronine
Thymocytes
Mast Cells
Confocal Microscopy
Vitamins
Flow Cytometry
Animals

Keywords

  • Hormonal imprinting
  • Hormones
  • Perinatal treatment
  • Vitamins A and D
  • White blood cells

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Cell Biology

Cite this

Impact of neonatal imprinting with vitamin A or D on the hormone content of rat immune cells. / Csaba, G.; Kovács, Peter; Pállinger, E.

In: Cell Biochemistry and Function, Vol. 25, No. 6, 11.2007, p. 717-721.

Research output: Contribution to journalArticle

@article{1218f98bace7412d901042dbcdd4191b,
title = "Impact of neonatal imprinting with vitamin A or D on the hormone content of rat immune cells",
abstract = "Neonatal single vitamin A (retinol; 3 mg) or vitamin D3 (cholecalciferol; 0.05 mg) treatment (imprinting) was done in male and female rats and 2 months later the endorphin, triiodothyronine (T3) and ACTH content of immune cells (peritoneal lymphocytes, monocyte-granulocyte- macrophage group [mo-gran], mast cells and thymic lymphocytes) were studied immunocytochemically by using flow cytometry and confocal microscopy. The T 3 content was significantly decreased in peritoneal lymphocytes and in mo-gran and the endorphin content decreased in thymocytes of male animals, while ACTH was decreased in female lymphocytes and mo-gran. Vitamin D treatment was absolutely ineffective. The imprinting effects of vitamins A and D and their differences are discussed. The results call attention to the possible harmful effect of vitamin treatments during the perinatal critical period.",
keywords = "Hormonal imprinting, Hormones, Perinatal treatment, Vitamins A and D, White blood cells",
author = "G. Csaba and Peter Kov{\'a}cs and E. P{\'a}llinger",
year = "2007",
month = "11",
doi = "10.1002/cbf.1381",
language = "English",
volume = "25",
pages = "717--721",
journal = "Cell Biochemistry and Function",
issn = "0263-6484",
publisher = "John Wiley and Sons Ltd",
number = "6",

}

TY - JOUR

T1 - Impact of neonatal imprinting with vitamin A or D on the hormone content of rat immune cells

AU - Csaba, G.

AU - Kovács, Peter

AU - Pállinger, E.

PY - 2007/11

Y1 - 2007/11

N2 - Neonatal single vitamin A (retinol; 3 mg) or vitamin D3 (cholecalciferol; 0.05 mg) treatment (imprinting) was done in male and female rats and 2 months later the endorphin, triiodothyronine (T3) and ACTH content of immune cells (peritoneal lymphocytes, monocyte-granulocyte- macrophage group [mo-gran], mast cells and thymic lymphocytes) were studied immunocytochemically by using flow cytometry and confocal microscopy. The T 3 content was significantly decreased in peritoneal lymphocytes and in mo-gran and the endorphin content decreased in thymocytes of male animals, while ACTH was decreased in female lymphocytes and mo-gran. Vitamin D treatment was absolutely ineffective. The imprinting effects of vitamins A and D and their differences are discussed. The results call attention to the possible harmful effect of vitamin treatments during the perinatal critical period.

AB - Neonatal single vitamin A (retinol; 3 mg) or vitamin D3 (cholecalciferol; 0.05 mg) treatment (imprinting) was done in male and female rats and 2 months later the endorphin, triiodothyronine (T3) and ACTH content of immune cells (peritoneal lymphocytes, monocyte-granulocyte- macrophage group [mo-gran], mast cells and thymic lymphocytes) were studied immunocytochemically by using flow cytometry and confocal microscopy. The T 3 content was significantly decreased in peritoneal lymphocytes and in mo-gran and the endorphin content decreased in thymocytes of male animals, while ACTH was decreased in female lymphocytes and mo-gran. Vitamin D treatment was absolutely ineffective. The imprinting effects of vitamins A and D and their differences are discussed. The results call attention to the possible harmful effect of vitamin treatments during the perinatal critical period.

KW - Hormonal imprinting

KW - Hormones

KW - Perinatal treatment

KW - Vitamins A and D

KW - White blood cells

UR - http://www.scopus.com/inward/record.url?scp=38449100796&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38449100796&partnerID=8YFLogxK

U2 - 10.1002/cbf.1381

DO - 10.1002/cbf.1381

M3 - Article

VL - 25

SP - 717

EP - 721

JO - Cell Biochemistry and Function

JF - Cell Biochemistry and Function

SN - 0263-6484

IS - 6

ER -