Impact of neonatal benzpyrene pretreatment (imprinting) on the hepatic 3H-benzpyrene intake and output in adult rat liver. Investigation into the hepatic localization of benzpyrene in adult rats.

A. K. Fülöp, G. Csaba

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

One hour after treatment with 3H-benzpyrene, grains appeared for the most part above the hepatocellular surface, heterochromatin and dense vacuoles, whereas 24 h later they were associated mainly with the dense vacuoles and smooth-surfaced endoplasmic reticulum and only, a few were still present above the heterochromatin. Neonatal pretreatment (imprinting) with benzpyrene accounted for an earlier appearance of benzpyrene in the hepatocytes relative to the non-pretreated control, but while labelled benzpyrene had practically disappeared from the liver of imprinted rats within 24 h, it still persisted in the liver of control rats at a level approximating the 4 h value.

Original languageEnglish
Pages (from-to)279-285
Number of pages7
JournalActa microbiologica Hungarica
Volume39
Issue number4
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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