Impact of infrared laser light-induced ablation at different wavelengths on bovine intervertebral disc ex vivo

Evaluation with magnetic resonance imaging and histology

Zsolt Cselik, Mihály Aradi, Ronald A. Von Jako, Zsuzsanna Lelovics, Ivett Juhász, Zsolt Egyházi, P. Bogner, I. Repa, Attila Schwarcz

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background and Objective: Percutaneous laser disc decompression is commonly used to lower high pressure in the nucleus pulposus in degenerative disc diseases. The aim of this study was to investigate the impact of diode laser disc decompression at different wavelengths (980-nm vs. 1,470-nm, i.e., different water absorption characteristics). Materials and Methods: To model decompression, a flexible laser quartz fiber inserted into the nucleus pulposus of ex vivo bovine spines using computer-assisted surgical navigation was utilized to vaporize tissue. The same energy (500 J) was delivered using both 980-nm and 1,470-nm wavelength lasers. To determine the different impact of the wavelengths before and after the procedure we evaluated the discs with MRI (T 1, T 2, diffusion maps) and with histopathology. Results: There were no visible changes on T 1 and T 2maps after 1,470-nm wavelength laser irradiation; however, the 980-nm wavelength caused significant changes on T 1(decrease) and T 2 (increase) in the vaporization zone at the site of the quartz fiber. Pathological findings showed carbonization and steam-bubble formation in addition to the T 1 and T 2 changes. No significant changes were detected in the value of apparent diffusion coefficient (ADC) measurements in intervertebral disc with the 980-nm wavelength, but significant ADC and T 1 signal increase was detected with the 1,470-nm wavelength when the whole nucleus pulposus was considered. Conclusion: The 1,470-nm laser light had an effect in the whole nucleus pulposus and not only at the site of the quartz fiber, whereas with the 980-nm laser irradiation, significant changes were demonstrated only at the application site.

Original languageEnglish
Pages (from-to)406-412
Number of pages7
JournalLasers in Surgery and Medicine
Volume44
Issue number5
DOIs
Publication statusPublished - Jul 2012

Fingerprint

Intervertebral Disc
Histology
Lasers
Magnetic Resonance Imaging
Light
Quartz
Decompression
Semiconductor Lasers
Volatilization
Steam
Spine
Pressure
Nucleus Pulposus
Water

Keywords

  • Ablation
  • Diode laser
  • Infrared light
  • Intervertebral disc
  • MRI
  • Percutaneous laser disc decompression (PLDD)
  • Stereotactic surgical navigation

ASJC Scopus subject areas

  • Surgery
  • Dermatology

Cite this

Impact of infrared laser light-induced ablation at different wavelengths on bovine intervertebral disc ex vivo : Evaluation with magnetic resonance imaging and histology. / Cselik, Zsolt; Aradi, Mihály; Von Jako, Ronald A.; Lelovics, Zsuzsanna; Juhász, Ivett; Egyházi, Zsolt; Bogner, P.; Repa, I.; Schwarcz, Attila.

In: Lasers in Surgery and Medicine, Vol. 44, No. 5, 07.2012, p. 406-412.

Research output: Contribution to journalArticle

Cselik, Zsolt ; Aradi, Mihály ; Von Jako, Ronald A. ; Lelovics, Zsuzsanna ; Juhász, Ivett ; Egyházi, Zsolt ; Bogner, P. ; Repa, I. ; Schwarcz, Attila. / Impact of infrared laser light-induced ablation at different wavelengths on bovine intervertebral disc ex vivo : Evaluation with magnetic resonance imaging and histology. In: Lasers in Surgery and Medicine. 2012 ; Vol. 44, No. 5. pp. 406-412.
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abstract = "Background and Objective: Percutaneous laser disc decompression is commonly used to lower high pressure in the nucleus pulposus in degenerative disc diseases. The aim of this study was to investigate the impact of diode laser disc decompression at different wavelengths (980-nm vs. 1,470-nm, i.e., different water absorption characteristics). Materials and Methods: To model decompression, a flexible laser quartz fiber inserted into the nucleus pulposus of ex vivo bovine spines using computer-assisted surgical navigation was utilized to vaporize tissue. The same energy (500 J) was delivered using both 980-nm and 1,470-nm wavelength lasers. To determine the different impact of the wavelengths before and after the procedure we evaluated the discs with MRI (T 1, T 2, diffusion maps) and with histopathology. Results: There were no visible changes on T 1 and T 2maps after 1,470-nm wavelength laser irradiation; however, the 980-nm wavelength caused significant changes on T 1(decrease) and T 2 (increase) in the vaporization zone at the site of the quartz fiber. Pathological findings showed carbonization and steam-bubble formation in addition to the T 1 and T 2 changes. No significant changes were detected in the value of apparent diffusion coefficient (ADC) measurements in intervertebral disc with the 980-nm wavelength, but significant ADC and T 1 signal increase was detected with the 1,470-nm wavelength when the whole nucleus pulposus was considered. Conclusion: The 1,470-nm laser light had an effect in the whole nucleus pulposus and not only at the site of the quartz fiber, whereas with the 980-nm laser irradiation, significant changes were demonstrated only at the application site.",
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AU - Lelovics, Zsuzsanna

AU - Juhász, Ivett

AU - Egyházi, Zsolt

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AU - Schwarcz, Attila

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AB - Background and Objective: Percutaneous laser disc decompression is commonly used to lower high pressure in the nucleus pulposus in degenerative disc diseases. The aim of this study was to investigate the impact of diode laser disc decompression at different wavelengths (980-nm vs. 1,470-nm, i.e., different water absorption characteristics). Materials and Methods: To model decompression, a flexible laser quartz fiber inserted into the nucleus pulposus of ex vivo bovine spines using computer-assisted surgical navigation was utilized to vaporize tissue. The same energy (500 J) was delivered using both 980-nm and 1,470-nm wavelength lasers. To determine the different impact of the wavelengths before and after the procedure we evaluated the discs with MRI (T 1, T 2, diffusion maps) and with histopathology. Results: There were no visible changes on T 1 and T 2maps after 1,470-nm wavelength laser irradiation; however, the 980-nm wavelength caused significant changes on T 1(decrease) and T 2 (increase) in the vaporization zone at the site of the quartz fiber. Pathological findings showed carbonization and steam-bubble formation in addition to the T 1 and T 2 changes. No significant changes were detected in the value of apparent diffusion coefficient (ADC) measurements in intervertebral disc with the 980-nm wavelength, but significant ADC and T 1 signal increase was detected with the 1,470-nm wavelength when the whole nucleus pulposus was considered. Conclusion: The 1,470-nm laser light had an effect in the whole nucleus pulposus and not only at the site of the quartz fiber, whereas with the 980-nm laser irradiation, significant changes were demonstrated only at the application site.

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