Impact of home- and center- based physical training program on cardio-metabolic health and IGF-1 level in elderly women

Dora Praksch, Barbara Sandor, David Kovacs, Peter Petrovics, Krisztina Kovacs, K. Tóth, Eszter Szabados

Research output: Contribution to journalArticle

Abstract

Background: Data in the literature concerning the effects of physical activity on lipid and IGF-1levels are controversial in postmenopausal women. The aim of the present study was to determine the combined effects of a 12 weeks home-based walking program aiming to achieve 10,000 steps daily and a center- based aerobic exercise training on functional capacity, some important cardio-metabolic parameters, IGF-1 level and psychological items among elderly female patients. Sixty female patients (67.4 ± 5 years) with moderate to high cardiovascular risk were randomly assigned either to an exercise training program for 12 weeks or to the control group. Results: Our organized training program resulted in a significantly improved daily physical activity (4232 [IQR: 3162-7219] to 8455 [IQR: 6757-11,488]; p < 0.001 ft-steps), functional capacity (MET) (8.17 ± 1.57 to 8.87 ± 1.76) (p = 0.002), metabolic status including total cholesterol (5.17 ± 1.13 to 4.77 ± 1.12 mmol/l), LDL cholesterol (3.37 ± 1.05 to 2.81 ± 0.98 mmol/l), triglyceride (1.68 ± 0.71 to 1.28 ± 0.71 mmol/l) and HgbA1c (6.24 ± 0.67 to 6.06 ± 0.58 mmol/l), as well as IGF-1 (59.68 ± 27.37 to 66.79 ± 22.74 ng/ml) levels (p < 0.05) in the training group. From psychological tests only physical functionality improved significantly (p = 0.03) in the training group. The training group significantly differed from the control group in four parameters including MET (p = 0.003), LDL-cholesterol (p = 0.046), triglyceride (p = 0.001) and IGF-1 levels (p < 0.001) after the intervention. Conclusion: The applied home-, and- center based training program effectively increased the daily physical activity of the elderly female patients and improved several cardio-metabolic parameters. Further investigations are needed on larger patient population to establish our findings and examine how these positive changes may decrease CV events and mortality.

Original languageEnglish
Article number13
JournalEuropean Review of Aging and Physical Activity
Volume16
Issue number1
DOIs
Publication statusPublished - Aug 8 2019

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Insulin-Like Growth Factor I
Exercise
Education
Health
LDL Cholesterol
Triglycerides
Psychological Tests
Control Groups
Walking
Cholesterol
Psychology
Lipids
Mortality
Population

Keywords

  • Cardio-metabolic health
  • Elderly female patients
  • IGF-1
  • Physical activity

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Impact of home- and center- based physical training program on cardio-metabolic health and IGF-1 level in elderly women. / Praksch, Dora; Sandor, Barbara; Kovacs, David; Petrovics, Peter; Kovacs, Krisztina; Tóth, K.; Szabados, Eszter.

In: European Review of Aging and Physical Activity, Vol. 16, No. 1, 13, 08.08.2019.

Research output: Contribution to journalArticle

Praksch, Dora ; Sandor, Barbara ; Kovacs, David ; Petrovics, Peter ; Kovacs, Krisztina ; Tóth, K. ; Szabados, Eszter. / Impact of home- and center- based physical training program on cardio-metabolic health and IGF-1 level in elderly women. In: European Review of Aging and Physical Activity. 2019 ; Vol. 16, No. 1.
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