Immunopathogenic mechanisms in experimental allergic encephalomyelitis

B. Kálmán, F. D. Lublin

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Experimental allergic encephalomyelitis, a cell-mediated autoimmune disease, continues to provide interesting data on the mechanisms subserving organ-specitic autoimmunity. The elements of the trimolecular complex have been further defined and the conserved molecular basis of the interaction between the T-cell receptor and the major histocompatibility complex class II-peptide antigen complex is better understood. This model also provides new insights into the cellular interactions within the brain during the course of the autoimmune inflammatory response.

Original languageEnglish
Pages (from-to)182-188
Number of pages7
JournalCurrent Opinion in Neurology and Neurosurgery
Volume6
Issue number2
Publication statusPublished - 1993

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Autoimmune Experimental Encephalomyelitis
Autoimmunity
Histocompatibility Antigens Class II
T-Cell Antigen Receptor
Major Histocompatibility Complex
Autoimmune Diseases
Peptides
Brain

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Immunopathogenic mechanisms in experimental allergic encephalomyelitis. / Kálmán, B.; Lublin, F. D.

In: Current Opinion in Neurology and Neurosurgery, Vol. 6, No. 2, 1993, p. 182-188.

Research output: Contribution to journalArticle

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