Immunological investigations in acute and chronic human pancreatitis

L. Antal, Mária Kávai, G. Szabó, Ildikó Sonkoly, Katalin Pálóczi, G. Szegedi, P. Sápy, I. Várhelyi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Follow-up immunological studies in 27 patients with acute pancreatitis of known etiology showed a significant elevation in the level of circulating immune complexes (IC). a significant inhibition in migration of leukocytes (with direct LMT) of patients and a significant decrease in the percentage of T-active, T-total peripheral lymphocytes and in the absolute count of peripheral T cells. Elevated circulating IC levels could been detected 3-4 weeks after the onset of acute pancreatitis. These immunological changes have still been demonstrated in a number of patients 7-14 months after recovery. We have found similar immunological alterations in patients with chronic pancreatitis as well. The possible causes and role of these long-term existing immunologic abnormalities are discussed.

Original languageEnglish
Pages (from-to)100-105
Number of pages6
JournalDigestion
Volume20
Issue number2
DOIs
Publication statusPublished - Jan 1 1980

Keywords

  • B lymphocytes
  • Immune complex
  • Lymphocyte migration test
  • Pancreatitis
  • T lymphocytes

ASJC Scopus subject areas

  • Gastroenterology

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