Immunological investigations in acute and chronic human pancreatitis

L. Antal, Mária Kávai, G. Szabó, Ildikó Sonkoly, K. Pálóczi, G. Szegedi, P. Sápy, I. Várhelyi

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Follow-up immunological studies in 27 patients with acute pancreatitis of known etiology showed a significant elevation in the level of circulating immune complexes (IC). a significant inhibition in migration of leukocytes (with direct LMT) of patients and a significant decrease in the percentage of T-active, T-total peripheral lymphocytes and in the absolute count of peripheral T cells. Elevated circulating IC levels could been detected 3-4 weeks after the onset of acute pancreatitis. These immunological changes have still been demonstrated in a number of patients 7-14 months after recovery. We have found similar immunological alterations in patients with chronic pancreatitis as well. The possible causes and role of these long-term existing immunologic abnormalities are discussed.

Original languageEnglish
Pages (from-to)100-105
Number of pages6
JournalDigestion
Volume20
Issue number2
DOIs
Publication statusPublished - 1980

Fingerprint

Chronic Pancreatitis
Antigen-Antibody Complex
Pancreatitis
Leukocytes
Lymphocytes
T-Lymphocytes

Keywords

  • B lymphocytes
  • Immune complex
  • Lymphocyte migration test
  • Pancreatitis
  • T lymphocytes

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Antal, L., Kávai, M., Szabó, G., Sonkoly, I., Pálóczi, K., Szegedi, G., ... Várhelyi, I. (1980). Immunological investigations in acute and chronic human pancreatitis. Digestion, 20(2), 100-105. https://doi.org/10.1159/000198425

Immunological investigations in acute and chronic human pancreatitis. / Antal, L.; Kávai, Mária; Szabó, G.; Sonkoly, Ildikó; Pálóczi, K.; Szegedi, G.; Sápy, P.; Várhelyi, I.

In: Digestion, Vol. 20, No. 2, 1980, p. 100-105.

Research output: Contribution to journalArticle

Antal, L, Kávai, M, Szabó, G, Sonkoly, I, Pálóczi, K, Szegedi, G, Sápy, P & Várhelyi, I 1980, 'Immunological investigations in acute and chronic human pancreatitis', Digestion, vol. 20, no. 2, pp. 100-105. https://doi.org/10.1159/000198425
Antal, L. ; Kávai, Mária ; Szabó, G. ; Sonkoly, Ildikó ; Pálóczi, K. ; Szegedi, G. ; Sápy, P. ; Várhelyi, I. / Immunological investigations in acute and chronic human pancreatitis. In: Digestion. 1980 ; Vol. 20, No. 2. pp. 100-105.
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