A significant proportion of unexplained recurrent spontaneous abortions (RSA) may be caused by immunological failure. A multicentric clinical programme started in August 2000 organized by the National Institute of Haematology and Immunology and the Dept. OB/GYN, Semmelweis University, Faculty of Health Sciences. The aim was to introduce a screening protocol for patients suffering in idiopathic habitual abortion in order to receive immunotherapy. The programme includes the scheme of intravenous immunoglobulin (IVIG) therapy for cases in which an immunological background was defined. 39 patients underwent this complex examinations until August 2001. Immunological screening was used at 32 women, 7 had other, non-immun etiology for RSA. We defined the immunological reason in 25 cases. 9 RSA patients with obvious immunological background were monitorized during their pregnancies applying immunotherapy. In 89% (8/9) of the cases the process was successful, with the result of healthy newborn. The introduction of RSA multicentric clinical programme seems to help clarifying the etiology of unexplained habitual abortions, and it gives a useful therapeutic protocol in RSA cases with immunological cause.
|Number of pages||4|
|Journal||Magyar Noorvosok Lapja|
|Publication status||Published - Jan 1 2002|
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynaecology