The development of a graft-versus-host reaction after hematopoietic stem cell transplantation is an important determinant of the transplant outcome. The existence of subsets of CD4+ helper T-lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for better understanding and improved management of the graft-versus-host reaction. It should allow improved prevention and treatment of graft-versus-host disease and the development of new strategies to enhance a graft-versus-leukemic relapse after transplantation.
|Translated title of the contribution||Immunologic bases of graft vs. host disease: 1997|
|Number of pages||6|
|Publication status||Published - Aug 31 1997|
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