Immunohistochemical localization of GABAergic cells in the developing human dorsal lateral geniculate nucleus

Shashi Wadhwa, József Hámori, Veena Bijlani

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5 Citations (Scopus)

Abstract

GABAergic neurons were demonstrated in the dorsal lateral geniculate nucleus (dLGN) of human foetuses of 21 weeks gestation using unlabelled antibodies against γ-aminobutyric acid (GABA). These inhibitory neurons are thus cytochemically identifiable prior to appearance of lamination, at a period when there is reportedly segregation of retinal afferents from both eyes and formation of morphologically defined synapses. Their presence in the prenatal period indicates that the morphological substrate responsible, in part, for the orientation sensitivity of the dLGN neurons exists before birth in man.

Original languageEnglish
Pages (from-to)97-101
Number of pages5
JournalNeuroscience Letters
Volume61
Issue number1-2
DOIs
Publication statusPublished - Oct 24 1985

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Keywords

  • GABAergic neuron
  • development
  • dorsal lateral geniculate nucleus
  • immunocytochemistry
  • man

ASJC Scopus subject areas

  • Neuroscience(all)

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