Immunoglobulin allotypes of European populations: I. Gm and Km(Inv) allotypic markers in Hungarians

M. S. Schanfield, J. Gergely, H. H. Fudenberg

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18 Citations (Scopus)

Abstract

The distribution of G1 m(f, z, a, and x), G3m(b0, b1, b3, c3, c5, g, s, and t) and Km(l) (formerly Inv[l]) allotypic markers have been examined in 184 Hungarians. The results indicate that the frequency of the immunoglobulin haplotypes Gmza;g, Gmzax;g, Gmf;b and Km1 is similar to the frequencies observed in surrounding populations. In addition, Hungarians were found to be polymorphic for the Oriental haplotype Gmza;bst, and had low frequencies of other uncommon haplotypes. Our data indicate that about 5% of the Hungarian genome is of Oriental origin.

Original languageEnglish
Pages (from-to)370-377
Number of pages8
JournalHuman heredity
Volume25
Issue number5
DOIs
Publication statusPublished - Jan 1 1975

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Keywords

  • Gm
  • Hungarian population studies
  • Km(Inv)

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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