Immune responses to isolated human cytomegalovirus envelope proteins

E. Gonczol, F. Hudecz, J. Ianacone, B. Dietzschold, S. Starr, S. A. Plotkin

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Abstract

A group of envelope proteins of human cytomegalovirus, gA protein, and two protein mixtures (58,000-molecular-weight [58K]-66K and 130K-66K), separated by serial columns prepared with anti-gA immunoglobulin G from sera of immunized guinea pigs, induced neutralizing antibodies and a cellular immune response in the animals. The gA is a disulfide-linked protein complex consisting of high-molecular-weight (> 200K), 130K-150K, and 55K-58K proteins.

Original languageEnglish
Pages (from-to)661-664
Number of pages4
JournalJournal of Virology
Volume58
Issue number2
Publication statusPublished - Nov 19 1986

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ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Cite this

Gonczol, E., Hudecz, F., Ianacone, J., Dietzschold, B., Starr, S., & Plotkin, S. A. (1986). Immune responses to isolated human cytomegalovirus envelope proteins. Journal of Virology, 58(2), 661-664.