Immune responses to isolated human cytomegalovirus envelope proteins

E. Gönczöl, F. Hudecz, J. Ianacone, B. Dietzschold, S. Starr, S. A. Plotkin

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

A group of envelope proteins of human cytomegalovirus, gA protein, and two protein mixtures (58,000-molecular-weight [58K]-66K and 130K-66K), separated by serial columns prepared with anti-gA immunoglobulin G from sera of immunized guinea pigs, induced neutralizing antibodies and a cellular immune response in the animals. The gA is a disulfide-linked protein complex consisting of high-molecular-weight (> 200K), 130K-150K, and 55K-58K proteins.

Original languageEnglish
Pages (from-to)661-664
Number of pages4
JournalJournal of Virology
Volume58
Issue number2
Publication statusPublished - 1986

Fingerprint

Human herpesvirus 5
Cytomegalovirus
immune response
Proteins
proteins
Molecular Weight
molecular weight
immunoglobulin G
Neutralizing Antibodies
sulfides
neutralizing antibodies
Cellular Immunity
Disulfides
cell-mediated immunity
guinea pigs
Guinea Pigs
Immunoglobulin G
Serum
animals

ASJC Scopus subject areas

  • Immunology

Cite this

Gönczöl, E., Hudecz, F., Ianacone, J., Dietzschold, B., Starr, S., & Plotkin, S. A. (1986). Immune responses to isolated human cytomegalovirus envelope proteins. Journal of Virology, 58(2), 661-664.

Immune responses to isolated human cytomegalovirus envelope proteins. / Gönczöl, E.; Hudecz, F.; Ianacone, J.; Dietzschold, B.; Starr, S.; Plotkin, S. A.

In: Journal of Virology, Vol. 58, No. 2, 1986, p. 661-664.

Research output: Contribution to journalArticle

Gönczöl, E, Hudecz, F, Ianacone, J, Dietzschold, B, Starr, S & Plotkin, SA 1986, 'Immune responses to isolated human cytomegalovirus envelope proteins', Journal of Virology, vol. 58, no. 2, pp. 661-664.
Gönczöl E, Hudecz F, Ianacone J, Dietzschold B, Starr S, Plotkin SA. Immune responses to isolated human cytomegalovirus envelope proteins. Journal of Virology. 1986;58(2):661-664.
Gönczöl, E. ; Hudecz, F. ; Ianacone, J. ; Dietzschold, B. ; Starr, S. ; Plotkin, S. A. / Immune responses to isolated human cytomegalovirus envelope proteins. In: Journal of Virology. 1986 ; Vol. 58, No. 2. pp. 661-664.
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