Imidazoline receptors: From discovery to antihypertensive therapy (facts and doubts)

C. Farsang, J. Kapocsi

Research output: Contribution to journalReview article

42 Citations (Scopus)

Abstract

The hypothesis and indirect evidence of imidazoline receptors has been promoted since some 15 years ago and it gave a substantial impetus for research in this field, resulting in a better understanding of neuronal and cardiovascular regulatory processes. The nomenclature of the imidazoline receptors has been accepted by international forums but no direct proof for the existence of these receptors has been published. Authors summarise the most important available data, including facts and doubts as far as the discovery, characterisation, and function of imidazoline receptors and their subtypes, the differences between imidazoline receptors and α-2 adrenoceptors, and also on their participation in regulatory processes.

Original languageEnglish
Pages (from-to)317-331
Number of pages15
JournalBrain Research Bulletin
Volume49
Issue number5
DOIs
Publication statusPublished - Jul 15 1999

    Fingerprint

Keywords

  • Cardiovascular regulation
  • Clonidine
  • Imidazolines
  • Moxonidine
  • Receptors
  • Rilmenidine

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this