Image processing-based automatic pupillometry on infrared videos

György Kalmár, Alexandra Büki, Gabriella Kékesi, Gyöngyi Horváth, László G. Nyúl

Research output: Contribution to journalArticle


Pupillometry is a non-invasive technique that can be used to objectively characterize pathophysiological changes involving the pupillary reex. It is essentially the measurement of the pupil diameter over time. Here, specially designed computer algorithms provide fast, reliable and reproducible solutions for the analysis. These methods use a priori information about the shape and color of the pupil. Our study focuses on measuring the diameter and dynamics of the pupils of rats with schizophrenia using videos recorded with a modified digital camera under infrared (IR) illumination. We developed a novel, robust method that measures the size of a pupil even under poor circumstances (noise, blur, reections and occlusions). We compare our results with measurements obtained using manual annotation.

Original languageEnglish
Pages (from-to)599-613
Number of pages15
JournalActa Cybernetica
Issue number2
Publication statusPublished - Jan 1 2017



  • Energy attenuation
  • Pupillometry
  • Ray propagation

ASJC Scopus subject areas

  • Software
  • Computer Science (miscellaneous)
  • Computer Vision and Pattern Recognition
  • Management Science and Operations Research
  • Information Systems and Management
  • Electrical and Electronic Engineering

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