IgA content of washed red blood cell concentrates

C. Baróti Tóth, J. Krámer, J. Pinter, M. Thék, J. E. Szabó

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Saline-washed red blood cell (RBC) concentrates are largely depleted of leukocytes, microaggregates, and nearly of all plasma originally contained in the blood unit. Our aim was to determine the concentration of the eliminated IgA and total protein in the buffy coat and plasma removed RBC concentrate before and after a sequential dilution-centrifugation washing procedure. 75.3% protein, and 99% IgA were eliminated by the washing process used. The recovery of red blood cells was 87.2%. Our results have led to the conclusion that two sequential washings seem to guarantee an IgA level of less than 0.2 mg/unit to meet the recommendations of the Council of Europe. Additional advantages of washing include low levels of extracellular hemoglobin, metabolic waste products and debris in the supernatant.

Original languageEnglish
Pages (from-to)13-14
Number of pages2
JournalVox Sanguinis
Volume74
Issue number1
DOIs
Publication statusPublished - 1998

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Immunoglobulin A
Erythrocytes
Waste Products
Centrifugation
Hemoglobins
Proteins
Leukocytes

ASJC Scopus subject areas

  • Hematology

Cite this

Baróti Tóth, C., Krámer, J., Pinter, J., Thék, M., & Szabó, J. E. (1998). IgA content of washed red blood cell concentrates. Vox Sanguinis, 74(1), 13-14. https://doi.org/10.1159/000030895

IgA content of washed red blood cell concentrates. / Baróti Tóth, C.; Krámer, J.; Pinter, J.; Thék, M.; Szabó, J. E.

In: Vox Sanguinis, Vol. 74, No. 1, 1998, p. 13-14.

Research output: Contribution to journalArticle

Baróti Tóth, C, Krámer, J, Pinter, J, Thék, M & Szabó, JE 1998, 'IgA content of washed red blood cell concentrates', Vox Sanguinis, vol. 74, no. 1, pp. 13-14. https://doi.org/10.1159/000030895
Baróti Tóth, C. ; Krámer, J. ; Pinter, J. ; Thék, M. ; Szabó, J. E. / IgA content of washed red blood cell concentrates. In: Vox Sanguinis. 1998 ; Vol. 74, No. 1. pp. 13-14.
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