Idiopathic thrombocytopenic purpura: examination of cellular immunity with homologous platelet antigen in vitro

M. Balazs, T. Burger, A. Pár, I. Palka, G. Deák

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Abstract

Lymphocyte transformation, as a cell mediated immune reaction to specific (platelet) and nonspecific (phytohemagglutinin) stimulants has been studied in the lymphocyte cultures of 12 patients suffering from idiopathic thrombocytopenic purpura (ITP) and in that of 10 normal subjects. The platelet antigen induced lymphocyte transformation in a large number of the patients but not in the normal subjects. This is indicative of the cellular immunity which plays a role in the pathomechanism of ITP. The method seems suitable for diagnostic use.

Original languageEnglish
Pages (from-to)33-38
Number of pages6
JournalActa Medica Academiae Scientiarum Hungaricae
Volume30
Issue number1-2
Publication statusPublished - 1973

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Idiopathic Thrombocytopenic Purpura
Lymphocyte Activation
Cellular Immunity
Blood Platelets
Antigens
Phytohemagglutinins
Lymphocytes
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

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Idiopathic thrombocytopenic purpura : examination of cellular immunity with homologous platelet antigen in vitro. / Balazs, M.; Burger, T.; Pár, A.; Palka, I.; Deák, G.

In: Acta Medica Academiae Scientiarum Hungaricae, Vol. 30, No. 1-2, 1973, p. 33-38.

Research output: Contribution to journalArticle

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