Identification of the Ulex europaeus agglutinin-I-binding protein as a unique glycoform of the neural cell adhesion molecule in the olfactory sensory axons of adult rats

Aurelian Pestean, István Krizbai, Herma Böttcher, Árpád Párducz, Ferenc Joó, Joachim R. Wolff

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Histochemical localization of two lectins, Ulex europaeus agglutinin-I (UEA-I) and Tetragonolobus purpureus (TPA), was studied in the olfactory bulb of adult rats. In contrast to TPA, UEA-I detected a fucosylated glycoprotein that is only present in the surface membranes of olfactory sensory cells including the whole course of their neurites up to the final arborization in glomeruli. Immunoblotting revealed that UEA-I binds specifically to a protein of 205 kDa, while TPA stains several other glycoproteins. Affinity chromatography with the use of a UEA-I column identified the 205 kDa protein as a glycoform of neural cell adhesion molecule (N-CAM), specific for the rat olfactory sensory nerves.

Original languageEnglish
Pages (from-to)117-120
Number of pages4
JournalNeuroscience Letters
Issue number2
Publication statusPublished - Aug 4 1995



  • Lectins
  • Neural cell adhesion molecule
  • Olfactory bulb
  • Ulex europaeus agglutinin-I binding

ASJC Scopus subject areas

  • Neuroscience(all)

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