The focus of this mini-review is to identify non-toxic compounds isolated from natural sources (plants) that exhibit specific activity against efflux pumps of specific multidrug-resistant (MDR) cancer cell lines, inhibit proliferation of the MDR cancer cell lines and inhibit the activity of overexpressed efflux pumps of the MDR cancer cell line.
- Induction of apoptosis
- Inhibition of P-glycoprotein (ABCB1)
- Multidrug-resistant cancer cell lines
- Non-toxic compounds isolated from natural sources (plants)
- Reversal of multidrug resistance
ASJC Scopus subject areas
- Cancer Research