Identification of a receptor for [32P]inositol-1,4,5-trisphosphate in saponin-permeabilized rabbit peritoneal neutrophils

P. G. Bradford, A. Spät, R. P. Rubin

Research output: Contribution to journalArticle

Abstract

In summary, the data indicate a specific binding site for (1,4,5)IP3 in saponin-permeabilized rabbit neutrophils. The binding is saturable and reversible and, moreover, occurs over a concentration range that is shown to release Ca2+ from nonmitochondrial stores in the same cell preparation.

Original languageEnglish
Pages (from-to)91-94
Number of pages4
JournalAnnals of the New York Academy of Sciences
Volume494
Publication statusPublished - 1987

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Inositol 1,4,5-Trisphosphate Receptors
Inositol 1,4,5-Trisphosphate
Saponins
Neutrophils
Binding Sites
Rabbits
Rabbit
Cells
Summary

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

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abstract = "In summary, the data indicate a specific binding site for (1,4,5)IP3 in saponin-permeabilized rabbit neutrophils. The binding is saturable and reversible and, moreover, occurs over a concentration range that is shown to release Ca2+ from nonmitochondrial stores in the same cell preparation.",
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AU - Bradford, P. G.

AU - Spät, A.

AU - Rubin, R. P.

PY - 1987

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AB - In summary, the data indicate a specific binding site for (1,4,5)IP3 in saponin-permeabilized rabbit neutrophils. The binding is saturable and reversible and, moreover, occurs over a concentration range that is shown to release Ca2+ from nonmitochondrial stores in the same cell preparation.

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