Identification of a novel canine norovirus

Livia Bodnar, Eleonora Lorusso, Barbara Di Martino, Cristiana Catella, Gianvito Lanave, Gabriella Elia, Krisztián Bányai, Canio Buonavoglia, Vito Martella

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

By screening a collection of fecal samples from young dogs from different European countries, noroviruses (NoVs) were found in 13/294 (4.4%) animals with signs of enteritis whilst they were not detected in healthy dogs (0/42). An informative portion of the genome (3.4 kb at the 3′ end) was generated for four NoV strains. In the capsid protein VP1 region, strains 63.15/2015/ITA and FD53/2007/ITA were genetically related to the canine GVI.2 strain C33/Viseu/2007/PRT (97.4–98.6% nt and 90.3–98.6% aa). Strain FD210/2007/ITA displayed the highest identity to the GVI.1 canine strain Bari/91/2007/ITA (88.0% nt and 95.0% aa). Strain 5010/2009/ITA displayed only 66.6–67.6% nt and 75.5–81.6% aa identities to the GVI.1 canine strains FD210/2007/ITA and Bari/91/2007/ITA and the GVI feline strain M49-1/2012/JPN. Identity to the other canine/feline NoVs strains in the VP1 was lower than 67.6% nt and 62.7% aa. Based on the full-length VP1 amino acid sequence and the criteria proposed for distinction of NoV genotypes, the canine NoV 5010/2009/ITA could represent the prototype of a third GVI genotype, thus providing further evidence for the genetic heterogeneity of NoVs in carnivores.

Original languageEnglish
Pages (from-to)75-81
Number of pages7
JournalInfection, Genetics and Evolution
Volume52
DOIs
Publication statusPublished - Aug 1 2017

Keywords

  • Dogs
  • Enteritis
  • Genogroup VI
  • Norovirus

ASJC Scopus subject areas

  • Microbiology
  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics
  • Microbiology (medical)
  • Infectious Diseases

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  • Cite this

    Bodnar, L., Lorusso, E., Di Martino, B., Catella, C., Lanave, G., Elia, G., Bányai, K., Buonavoglia, C., & Martella, V. (2017). Identification of a novel canine norovirus. Infection, Genetics and Evolution, 52, 75-81. https://doi.org/10.1016/j.meegid.2017.04.020