ICSI versus IMSI

Zsolt Peter Nagy, Pierre Vanderzwalmen

Research output: Chapter in Book/Report/Conference proceedingChapter


Intracytoplasmic sperm injection (ICSI) was introduced in the clinical practice in 1992, to overcome male-factor infertility and in failed conventional IVF cases. Today ICSI is used across the world in most IVF cases, for almost all indications of infertility and it provides consistently high pregnancy rates. Recent studies indicated, that ICSI outcomes may be further improved if the sperm selected for microinjection is examined under very high magnification for morphological characteristics. This lead to the introduction of IMSI which provided the advantage to use the morphologically most adequate sperm to perform ICSI.

Original languageEnglish
Title of host publicationEncyclopedia of Reproduction
Number of pages7
ISBN (Electronic)9780128151457
Publication statusPublished - Jan 1 2018


  • Assisted reproductive technology (ART)
  • Embryo
  • Fertilization
  • In vitro fertilization (IVF)
  • Insemination
  • Intracytoplasmic morphologically selected sperm injection (IMSI)
  • Intracytoplasmic sperm injection (ICSI)
  • Motile sperm organelle morphology examination (MSOME)
  • Oocyte
  • Pregnancy
  • Sperm

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Nagy, Z. P., & Vanderzwalmen, P. (2018). ICSI versus IMSI. In Encyclopedia of Reproduction (pp. 152-158). Elsevier. https://doi.org/10.1016/B978-0-12-801238-3.64854-7