Hyposthenuria: Sandor Koranyi's concept of renal insufficiency

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Abstract

Around the turn of the 19th century, the Hunarian physiologist and clinician, Sandor Koranyi, started to use physicochemical methods to estimate renal function. In parallel with the deterioration of renal function, he found characteristic changes in the freezing point depression of urine, which he termed hyposthenuria. On the basis of these findings, he was the first to introduce the functional concept of renal insufficiency.

Original languageEnglish
Pages (from-to)320-322
Number of pages3
JournalAmerican Journal of Nephrology
Volume19
Issue number2
DOIs
Publication statusPublished - Mar 1 1999

Keywords

  • Freezing point depression
  • Koranyi
  • Renal insufficiency
  • Urine

ASJC Scopus subject areas

  • Nephrology

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