Hypertriglyceridemia causes more severe course of acute pancreatitis

Tamás Baranyai, Viktória Terzin, Ágota Vajda, T. Wittmann, L. Czakó

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Aim: To assess the clinical features and management of hypertriglyceridemia (HTG)-induced acute pancreatitis (AP). Patients & methods: Patients with AP and serum triglyceride levels of >11.3 mmol/l were included. Results: HTG-induced AP accounted for 6.28% of the total number of AP cases. HTG-induced AP patients were significantly younger and there was a male preponderance compared with non-HTG-induced pancreatitic patients. Antilipemic therapy lowered triglyceride levels from 44.78 ± 6.26 to 3.59 ± 0.3 mmol/l in the HTG-induced AP group. Amylase levels were elevated three-times over normal levels in only 23.1% of HTG-induced AP patients. Severe prognosis, pancreatic necrosis, sepsis and local complications were more frequent and the length of hospitalization was significantly longer in the HTG-induced AP compared with AP with other etiologies. Conclusion: HTG-induced AP seems to be more severe than AP of other causes. Levels of serum amylase may be normal or only minimally elevated.

Original languageEnglish
Pages (from-to)731-736
Number of pages6
JournalClinical Lipidology
Volume7
Issue number6
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Hypertriglyceridemia
Pancreatitis
Amylases
Triglycerides
Hypolipidemic Agents
Serum
Sepsis
Hospitalization
Necrosis

Keywords

  • acute pancreatitis
  • amylase
  • heparin
  • hypertriglyceridemia
  • insulin
  • lipase
  • plasmapheresis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

Hypertriglyceridemia causes more severe course of acute pancreatitis. / Baranyai, Tamás; Terzin, Viktória; Vajda, Ágota; Wittmann, T.; Czakó, L.

In: Clinical Lipidology, Vol. 7, No. 6, 12.2012, p. 731-736.

Research output: Contribution to journalArticle

Baranyai, Tamás ; Terzin, Viktória ; Vajda, Ágota ; Wittmann, T. ; Czakó, L. / Hypertriglyceridemia causes more severe course of acute pancreatitis. In: Clinical Lipidology. 2012 ; Vol. 7, No. 6. pp. 731-736.
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