Hyperglycaemic hemi ballismus: Implications from connectivity analysis for cognitive impairments

Zsigmond Tamás Kincses, Dávid Vadász, Dezso Németh, Karolina Janacsek, Nikoletta Szabó, Lívia Dézsi, Magor Babos, E. Vörös, L. Vécsei

Research output: Contribution to journalArticle

Abstract

Hyperglycaemia induced movement disorders, such as hemiballism are rare disorders. The syndrome is characterised by the triad of hemiballism, contralateral Tl-hyperintense striatal lesion and non-ketotic hyperglycaemia. Here we report a patient with untreated diabetes presenting with acute onset of hemiballism. MRI revealed Tl hyperintensity of the head of the caudate nucleus and the anterior putamen. The patient also had acantocytosis. Based on the detailed examination of the neuroradiological results and earlier findings we will imply on the pathomechanism. Based on previous findings microhemorrhages, extensive mineralisation, gemistocytic astrocytosis might play role in the development of the imaging signs. The connectivity pattern of the striatal lesion showed extensive connections to the frontal cortex. In coexistence with that the most severe impairment was found on the phonemic verbal fluency task measuring frontal executive functions.

Original languageEnglish
Pages (from-to)417-421
Number of pages5
JournalIdeggyogyaszati Szemle
Volume68
Issue number11-12
DOIs
Publication statusPublished - Nov 30 2015

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Keywords

  • Frontal executive functions
  • Hemiballism
  • Hyperglycaemia

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Kincses, Z. T., Vadász, D., Németh, D., Janacsek, K., Szabó, N., Dézsi, L., Babos, M., Vörös, E., & Vécsei, L. (2015). Hyperglycaemic hemi ballismus: Implications from connectivity analysis for cognitive impairments. Ideggyogyaszati Szemle, 68(11-12), 417-421. https://doi.org/10.18071/isz.68.417