Hyperglycaemic hemi ballismus: Implications from connectivity analysis for cognitive impairments

Zsigmond Tamás Kincses, Dávid Vadász, Dezso Németh, Karolina Janacsek, Nikoletta Szabó, Lívia Dézsi, Magor Babos, E. Vörös, L. Vécsei

Research output: Contribution to journalArticle

Abstract

Hyperglycaemia induced movement disorders, such as hemiballism are rare disorders. The syndrome is characterised by the triad of hemiballism, contralateral Tl-hyperintense striatal lesion and non-ketotic hyperglycaemia. Here we report a patient with untreated diabetes presenting with acute onset of hemiballism. MRI revealed Tl hyperintensity of the head of the caudate nucleus and the anterior putamen. The patient also had acantocytosis. Based on the detailed examination of the neuroradiological results and earlier findings we will imply on the pathomechanism. Based on previous findings microhemorrhages, extensive mineralisation, gemistocytic astrocytosis might play role in the development of the imaging signs. The connectivity pattern of the striatal lesion showed extensive connections to the frontal cortex. In coexistence with that the most severe impairment was found on the phonemic verbal fluency task measuring frontal executive functions.

Original languageEnglish
Pages (from-to)417-421
Number of pages5
JournalIdeggyogyaszati Szemle
Volume68
Issue number11-12
DOIs
Publication statusPublished - Nov 30 2015

Fingerprint

Dyskinesias
Corpus Striatum
Hyperglycemia
Gliosis
Caudate Nucleus
Putamen
Executive Function
Movement Disorders
Frontal Lobe
Cognitive Dysfunction

Keywords

  • Frontal executive functions
  • Hemiballism
  • Hyperglycaemia

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Hyperglycaemic hemi ballismus : Implications from connectivity analysis for cognitive impairments. / Kincses, Zsigmond Tamás; Vadász, Dávid; Németh, Dezso; Janacsek, Karolina; Szabó, Nikoletta; Dézsi, Lívia; Babos, Magor; Vörös, E.; Vécsei, L.

In: Ideggyogyaszati Szemle, Vol. 68, No. 11-12, 30.11.2015, p. 417-421.

Research output: Contribution to journalArticle

Kincses, ZT, Vadász, D, Németh, D, Janacsek, K, Szabó, N, Dézsi, L, Babos, M, Vörös, E & Vécsei, L 2015, 'Hyperglycaemic hemi ballismus: Implications from connectivity analysis for cognitive impairments', Ideggyogyaszati Szemle, vol. 68, no. 11-12, pp. 417-421. https://doi.org/10.18071/isz.68.417
Kincses ZT, Vadász D, Németh D, Janacsek K, Szabó N, Dézsi L et al. Hyperglycaemic hemi ballismus: Implications from connectivity analysis for cognitive impairments. Ideggyogyaszati Szemle. 2015 Nov 30;68(11-12):417-421. https://doi.org/10.18071/isz.68.417
Kincses, Zsigmond Tamás ; Vadász, Dávid ; Németh, Dezso ; Janacsek, Karolina ; Szabó, Nikoletta ; Dézsi, Lívia ; Babos, Magor ; Vörös, E. ; Vécsei, L. / Hyperglycaemic hemi ballismus : Implications from connectivity analysis for cognitive impairments. In: Ideggyogyaszati Szemle. 2015 ; Vol. 68, No. 11-12. pp. 417-421.
@article{b8e5e6805a2346e8800dd6d25e3b1fb5,
title = "Hyperglycaemic hemi ballismus: Implications from connectivity analysis for cognitive impairments",
abstract = "Hyperglycaemia induced movement disorders, such as hemiballism are rare disorders. The syndrome is characterised by the triad of hemiballism, contralateral Tl-hyperintense striatal lesion and non-ketotic hyperglycaemia. Here we report a patient with untreated diabetes presenting with acute onset of hemiballism. MRI revealed Tl hyperintensity of the head of the caudate nucleus and the anterior putamen. The patient also had acantocytosis. Based on the detailed examination of the neuroradiological results and earlier findings we will imply on the pathomechanism. Based on previous findings microhemorrhages, extensive mineralisation, gemistocytic astrocytosis might play role in the development of the imaging signs. The connectivity pattern of the striatal lesion showed extensive connections to the frontal cortex. In coexistence with that the most severe impairment was found on the phonemic verbal fluency task measuring frontal executive functions.",
keywords = "Frontal executive functions, Hemiballism, Hyperglycaemia",
author = "Kincses, {Zsigmond Tam{\'a}s} and D{\'a}vid Vad{\'a}sz and Dezso N{\'e}meth and Karolina Janacsek and Nikoletta Szab{\'o} and L{\'i}via D{\'e}zsi and Magor Babos and E. V{\"o}r{\"o}s and L. V{\'e}csei",
year = "2015",
month = "11",
day = "30",
doi = "10.18071/isz.68.417",
language = "English",
volume = "68",
pages = "417--421",
journal = "Ideggyogyaszati Szemle",
issn = "0019-1442",
publisher = "Ifjusagi Lap-es Konyvkiado Vallalat",
number = "11-12",

}

TY - JOUR

T1 - Hyperglycaemic hemi ballismus

T2 - Implications from connectivity analysis for cognitive impairments

AU - Kincses, Zsigmond Tamás

AU - Vadász, Dávid

AU - Németh, Dezso

AU - Janacsek, Karolina

AU - Szabó, Nikoletta

AU - Dézsi, Lívia

AU - Babos, Magor

AU - Vörös, E.

AU - Vécsei, L.

PY - 2015/11/30

Y1 - 2015/11/30

N2 - Hyperglycaemia induced movement disorders, such as hemiballism are rare disorders. The syndrome is characterised by the triad of hemiballism, contralateral Tl-hyperintense striatal lesion and non-ketotic hyperglycaemia. Here we report a patient with untreated diabetes presenting with acute onset of hemiballism. MRI revealed Tl hyperintensity of the head of the caudate nucleus and the anterior putamen. The patient also had acantocytosis. Based on the detailed examination of the neuroradiological results and earlier findings we will imply on the pathomechanism. Based on previous findings microhemorrhages, extensive mineralisation, gemistocytic astrocytosis might play role in the development of the imaging signs. The connectivity pattern of the striatal lesion showed extensive connections to the frontal cortex. In coexistence with that the most severe impairment was found on the phonemic verbal fluency task measuring frontal executive functions.

AB - Hyperglycaemia induced movement disorders, such as hemiballism are rare disorders. The syndrome is characterised by the triad of hemiballism, contralateral Tl-hyperintense striatal lesion and non-ketotic hyperglycaemia. Here we report a patient with untreated diabetes presenting with acute onset of hemiballism. MRI revealed Tl hyperintensity of the head of the caudate nucleus and the anterior putamen. The patient also had acantocytosis. Based on the detailed examination of the neuroradiological results and earlier findings we will imply on the pathomechanism. Based on previous findings microhemorrhages, extensive mineralisation, gemistocytic astrocytosis might play role in the development of the imaging signs. The connectivity pattern of the striatal lesion showed extensive connections to the frontal cortex. In coexistence with that the most severe impairment was found on the phonemic verbal fluency task measuring frontal executive functions.

KW - Frontal executive functions

KW - Hemiballism

KW - Hyperglycaemia

UR - http://www.scopus.com/inward/record.url?scp=84978040197&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84978040197&partnerID=8YFLogxK

U2 - 10.18071/isz.68.417

DO - 10.18071/isz.68.417

M3 - Article

C2 - 26821516

AN - SCOPUS:84978040197

VL - 68

SP - 417

EP - 421

JO - Ideggyogyaszati Szemle

JF - Ideggyogyaszati Szemle

SN - 0019-1442

IS - 11-12

ER -