Hydroxyl radical induced degradation of ibuprofen

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69 Citations (Scopus)

Abstract

Pulse radiolysis experiments were used to characterize the intermediates formed from ibuprofen during electron beam irradiation in a solution of 0.1mmoldm-3. For end product characterization 60Co γ-irradiation was used and the samples were evaluated either by taking their UV-vis spectra or by HPLC with UV or MS detection. The reactions of OH resulted in hydroxycyclohexadienyl type radical intermediates. The intermediates produced in further reactions hydroxylated the derivatives of ibuprofen as final products. The hydrated electron attacked the carboxyl group. Ibuprofen degradation is more efficient under oxidative conditions than under reductive conditions. The ecotoxicity of the solution was monitored by Daphnia magna standard microbiotest and Vibrio fischeri luminescent bacteria test. The toxic effect of the aerated ibuprofen solution first increased upon irradiation indicating a higher toxicity of the first degradation products, then decreased with increasing absorbed dose.

Original languageEnglish
Pages (from-to)286-292
Number of pages7
JournalScience of the Total Environment
Volume447
DOIs
Publication statusPublished - Mar 1 2013

Keywords

  • Advanced oxidation processes
  • Hydrated electron
  • Hydroxyl radical
  • Ibuprofen
  • Radiolysis

ASJC Scopus subject areas

  • Environmental Engineering
  • Environmental Chemistry
  • Waste Management and Disposal
  • Pollution

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