Hydrogenolysis of O-protected hydroxyoxetanes over palladium: An efficient method for a one-step ring opening and detritylation reaction

Ferenc Farkas, Angelika Thurner, Ervin Kovács, F. Faigl, L. Hegedûs

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

An efficient method for the palladium mediated hydrogenation of an optically active, O-protected hydroxyoxetane derivative has been developed. Using appropriate solvents, in a one-step reaction, optically active 1,4-diol was formed over a Pd/C catalyst, during hydrogenolytic ring opening and detritylation reactions.

Original languageEnglish
Pages (from-to)635-639
Number of pages5
JournalCatalysis Communications
Volume10
Issue number5
DOIs
Publication statusPublished - Jan 25 2009

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Hydrogenolysis
Palladium
Hydrogenation
Derivatives
Catalysts

Keywords

  • Catalytic hydrogenation
  • Chiral oxetanes
  • Hydrogenolysis
  • Optically active 1,4-diols
  • Palladium
  • Solvent effects

ASJC Scopus subject areas

  • Catalysis
  • Process Chemistry and Technology
  • Chemistry(all)

Cite this

Hydrogenolysis of O-protected hydroxyoxetanes over palladium : An efficient method for a one-step ring opening and detritylation reaction. / Farkas, Ferenc; Thurner, Angelika; Kovács, Ervin; Faigl, F.; Hegedûs, L.

In: Catalysis Communications, Vol. 10, No. 5, 25.01.2009, p. 635-639.

Research output: Contribution to journalArticle

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