Hydrogenation ofmethyl 3a-acetoxy-23-oxo-5b-cholan-24-oatecatalyzed by cinchona alkaloid-modified Pt-alumina catalyst

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3 Citations (Scopus)

Abstract

Methyl-3α-acetoxy-23-oxo-5β-cholan-24-oate is hydrogenated with 78% enantioselection at C23 atom over Pt-alumina catalyst modified with cinchona alkaloids, in liquid phase under mild experimental conditions (293-297 K, hydrogen pressure: 1 bar, concentration of modifiers: 0.1 mmol/L, solvent: THF).

Original languageEnglish
Pages (from-to)323-329
Number of pages7
JournalReaction Kinetics and Catalysis Letters
Volume86
Issue number2
DOIs
Publication statusPublished - Nov 2005

Fingerprint

Cinchona Alkaloids
alkaloids
Aluminum Oxide
Hydrogenation
hydrogenation
Hydrogen
liquid phases
Alumina
aluminum oxides
catalysts
Atoms
Catalysts
Liquids
hydrogen
atoms

Keywords

  • Cinchona alkaloids
  • Enantioselective
  • Hydrogenation
  • Platinumalumina
  • Steroids

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Catalysis

Cite this

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title = "Hydrogenation ofmethyl 3a-acetoxy-23-oxo-5b-cholan-24-oatecatalyzed by cinchona alkaloid-modified Pt-alumina catalyst",
abstract = "Methyl-3α-acetoxy-23-oxo-5β-cholan-24-oate is hydrogenated with 78{\%} enantioselection at C23 atom over Pt-alumina catalyst modified with cinchona alkaloids, in liquid phase under mild experimental conditions (293-297 K, hydrogen pressure: 1 bar, concentration of modifiers: 0.1 mmol/L, solvent: THF).",
keywords = "Cinchona alkaloids, Enantioselective, Hydrogenation, Platinumalumina, Steroids",
author = "K. Felf{\"o}ldi and I. Bucsi and Brigitta Kazi and M. Bart{\'o}k",
year = "2005",
month = "11",
doi = "10.1007/s11144-005-0328-9",
language = "English",
volume = "86",
pages = "323--329",
journal = "Reaction Kinetics, Mechanisms and Catalysis",
issn = "1878-5190",
publisher = "Springer Netherlands",
number = "2",

}

TY - JOUR

T1 - Hydrogenation ofmethyl 3a-acetoxy-23-oxo-5b-cholan-24-oatecatalyzed by cinchona alkaloid-modified Pt-alumina catalyst

AU - Felföldi, K.

AU - Bucsi, I.

AU - Kazi, Brigitta

AU - Bartók, M.

PY - 2005/11

Y1 - 2005/11

N2 - Methyl-3α-acetoxy-23-oxo-5β-cholan-24-oate is hydrogenated with 78% enantioselection at C23 atom over Pt-alumina catalyst modified with cinchona alkaloids, in liquid phase under mild experimental conditions (293-297 K, hydrogen pressure: 1 bar, concentration of modifiers: 0.1 mmol/L, solvent: THF).

AB - Methyl-3α-acetoxy-23-oxo-5β-cholan-24-oate is hydrogenated with 78% enantioselection at C23 atom over Pt-alumina catalyst modified with cinchona alkaloids, in liquid phase under mild experimental conditions (293-297 K, hydrogen pressure: 1 bar, concentration of modifiers: 0.1 mmol/L, solvent: THF).

KW - Cinchona alkaloids

KW - Enantioselective

KW - Hydrogenation

KW - Platinumalumina

KW - Steroids

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U2 - 10.1007/s11144-005-0328-9

DO - 10.1007/s11144-005-0328-9

M3 - Article

AN - SCOPUS:31344440832

VL - 86

SP - 323

EP - 329

JO - Reaction Kinetics, Mechanisms and Catalysis

JF - Reaction Kinetics, Mechanisms and Catalysis

SN - 1878-5190

IS - 2

ER -