Hydrogenation of pyrrole derivatives. Ii. Hydrogenations over supported noble metal catalysts

L. Hegedûs, Tibor Máthé, A. Tungler

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The heterogeneous catalytic hydrogenation of 1-methyl-2-pyrroleethanol resulted in 1-methyl-2-pyrrolidineethanol, an important and valuable pharmaceutical intermediate. Various noble metal catalysts on different supports have been screened. The best results were achieved with a carbon supported rhodium catalyst, in non-acidic medium, under mild reaction conditions (6 bar, room temperature). Ruthenium on carbon also showed high activity in this hydrogenation.

Original languageEnglish
Pages (from-to)407-414
Number of pages8
JournalApplied Catalysis A: General
Volume147
Issue number2
DOIs
Publication statusPublished - Dec 2 1996

Fingerprint

Pyrroles
Precious metals
Hydrogenation
Carbon
Derivatives
Rhodium
Catalysts
Ruthenium
Catalyst supports
Drug products
Thermodynamic properties
Pharmaceutical Preparations
Temperature

Keywords

  • 1-Methyl-2-pyrrolidineethanol
  • Heterogeneous catalytic hydrogenation
  • Rhodium
  • Ruthenium

ASJC Scopus subject areas

  • Catalysis
  • Process Chemistry and Technology

Cite this

Hydrogenation of pyrrole derivatives. Ii. Hydrogenations over supported noble metal catalysts. / Hegedûs, L.; Máthé, Tibor; Tungler, A.

In: Applied Catalysis A: General, Vol. 147, No. 2, 02.12.1996, p. 407-414.

Research output: Contribution to journalArticle

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