A Levodopa/Carbidopa intestinalis gél kezelés magyarországi tapasztalatai elorehaladott parkinson-kórban

Translated title of the contribution: Hungarian experiences with Levodopa/Carbidopa intestinal gel in the treatment of advanced parkinson's disease

Helga Nagy, Annamária Takáts, Adrián Tóth, Dániel Bereczki, Péter Klivényi, Lívia Dézsi, György Dibó, László Vécsei, Norbert Kovács, Zsuzsa Aschermann, Sámuel Komoly, Lajos Varannai, Gyöngyi Zemlényi, Attila Valikovics

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In the advanced Parkison's disease (PD) the late complications of levodopa therapy have to be considered: motor and/or non-motor fluctuations with or without disturbing dyskinesias. The non-motor fluctuations often influence the quality of life (QoL) in a much more negative way compared with the motor symptoms. In the treatment of advanced PD there are several device-aided methods-deep brain stimulation, apomorphine pump, levodopa/carbidopa intestinal gel (LCIG) - to improve the symptoms, the QoL, sometimes even in an individual, tailored custom form. The LCIG therapy was introduced in Hungary in 2011. Here we summarize the data of our patients: we have tested almost 60 patients and in 43 cases we have started this treatment. We analyze the duration of illness, levodopa therapy, motor and non-motor fluctuation of patients and present our experiences with the test phase and the chronic LCIG therapy via PEG/PEJ implantation. We paid attention to the surgery and device - depending side effects. Our experiences are similar to the international data. In patients selection "the right treatment, to the right patient, in the right time" is of importance.

Translated title of the contributionHungarian experiences with Levodopa/Carbidopa intestinal gel in the treatment of advanced parkinson's disease
Original languageHungarian
Pages (from-to)385-389
Number of pages5
JournalIdeggyogyaszati szemle
Volume67
Issue number11-12
Publication statusPublished - Nov 30 2014

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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