Humoral serotonin and dopamine modulate the feeding in the snail, Helix pomatia

L. Hernádi, L. Kárpáti, J. Gyori, A. Vehovszky, L. Hiripi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We investigated the effect of elevated levels of humoral 5HT and DA on the feeding latency of Helix pomatia, 1 day, 3 days and 10 days following satiation, by injecting monoamines into the haemocoel. HPLC assay of monoamines showed that both 5HT and DA are present in pmol/ml concentrations in the haemolymph of both starved and non-starved animals. Elevated levels of 5HT and DA were most effective at decreasing the feeding latency 10 days following satiation when DA decreased the feeding latency in a concentration dependent manner between 10-7 and 10-5 M whereas 5HT levels decreased the feeding latency only at 10-6 M but increased it at 10-5 M. Immunocytochemistry revealed that both 5HT3 and D1 receptor-like immuno-reactivity are present in cell bodies located in the same areas of the buccal ganglia. Our observations suggest that both humoral DA and 5HT mutually modulate the activity of the feeding CPG through neurons which have these receptors.

Original languageEnglish
Pages (from-to)39-46
Number of pages8
JournalActa Biologica Hungarica
Volume59
Issue numberSUPPL.
DOIs
Publication statusPublished - Jun 3 2008

Fingerprint

Helix (Snails)
Satiation
Helix pomatia
monoamines
satiety
dopamine
serotonin
snail
snails
Dopamine
Serotonin
hemocoel
receptors
Hemolymph
Cheek
immunocytochemistry
Ganglia
hemolymph
neurons
Immunohistochemistry

Keywords

  • 5HT3 receptor
  • Arousal
  • D1 receptor-motivation
  • Feeding latency

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Neurology
  • Agricultural and Biological Sciences(all)

Cite this

Humoral serotonin and dopamine modulate the feeding in the snail, Helix pomatia. / Hernádi, L.; Kárpáti, L.; Gyori, J.; Vehovszky, A.; Hiripi, L.

In: Acta Biologica Hungarica, Vol. 59, No. SUPPL., 03.06.2008, p. 39-46.

Research output: Contribution to journalArticle

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