Human pharmacokinetics of analgesics and methods for their determination in biological fluids

P. Miskolczi, L. Vereczkey

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The main pharmacokinetic data of analgesics - biological half-lives, apparent volumes of distribution, total body clearances - obtained in humans, and their clinical relevance are summarized. Special emphasis has been given to the analytical methods used for the quantitative determination of these drugs in biological fluids.

Original languageEnglish
Pages (from-to)209-226
Number of pages18
JournalJournal of Pharmaceutical and Biomedical Analysis
Volume3
Issue number3
DOIs
Publication statusPublished - 1985

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Pharmacokinetics
Analgesics
Fluids
Pharmaceutical Preparations

Keywords

  • bioavailability
  • buprenorphine
  • codeine
  • drug half-lives
  • ketamine
  • methdone
  • Morphine
  • p-aminophenol derivatives
  • pentazocine
  • pethidine
  • pharmacokinetics
  • plasma clearance
  • salicylic acid derivatives
  • volume of distribution.

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmaceutical Science

Cite this

Human pharmacokinetics of analgesics and methods for their determination in biological fluids. / Miskolczi, P.; Vereczkey, L.

In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 3, No. 3, 1985, p. 209-226.

Research output: Contribution to journalArticle

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