Human gyogyszermetabolizalo enzimek I. Oxidacios enzimek

Translated title of the contribution: Human drug metabolizing enzymes I. Oxidative enzymes

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

In this review we focus on human oxidative enzymes that are responsible for the metabolism of xenobiotics. More and more publications prove that the reactions catalysed by these enzymes very often lead to activated molecules that may attack macromolecules (proteins, RNAs, DNAs), resulting in toxicity (liver, neuro-, embryotoxicity, allergy, carcinogenecity). We have summarised the data available on these enzymes, concerning their catalytic profile and specificity, inhibition, induction properties, their possible role in the generation of toxic compounds, their importance in clinical practice and drug development.

Original languageHungarian
Pages (from-to)276-283
Number of pages8
JournalActa Pharmaceutica Hungarica
Volume68
Issue number5
Publication statusPublished - Sep 1998

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Enzymes
Pharmaceutical Preparations
Poisons
Xenobiotics
Publications
Hypersensitivity
RNA
Liver
DNA
Proteins

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Human gyogyszermetabolizalo enzimek I. Oxidacios enzimek. / Vereczkey, L.; Monostory, K.; Veres, Z.

In: Acta Pharmaceutica Hungarica, Vol. 68, No. 5, 09.1998, p. 276-283.

Research output: Contribution to journalArticle

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