Human gyogyszermetabolizalo enzimek I. Oxidacios enzimek

Translated title of the contribution: Human drug metabolizing enzymes I. Oxidative enzymes

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

In this review we focus on human oxidative enzymes that are responsible for the metabolism of xenobiotics. More and more publications prove that the reactions catalysed by these enzymes very often lead to activated molecules that may attack macromolecules (proteins, RNAs, DNAs), resulting in toxicity (liver, neuro-, embryotoxicity, allergy, carcinogenecity). We have summarised the data available on these enzymes, concerning their catalytic profile and specificity, inhibition, induction properties, their possible role in the generation of toxic compounds, their importance in clinical practice and drug development.

Translated title of the contributionHuman drug metabolizing enzymes I. Oxidative enzymes
Original languageHungarian
Pages (from-to)276-283
Number of pages8
JournalActa pharmaceutica Hungarica
Volume68
Issue number5
Publication statusPublished - Sep 1 1998

ASJC Scopus subject areas

  • Pharmaceutical Science

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