HPLC monitoring of the microsomal stability of rutin and quercetin

E. Szőke, G. Petroianu, K. Tekes, B. Benko, P. Szegi, R. Laufer, G. Veress

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Reversed-phase HPLC has been used to monitor the concentration of the two major Chamomile components rutin and quercetin during rat liver microsomal treatment. The possibility of microsomal oxidative metabolism or stability of these two components was examined using a guard-column without any clean-up. The concentration of quercetin decreased when exposed to rat liver microsomal media whereas the rutin concentration did not change significantly over one hour of treatment.

Original languageEnglish
Pages (from-to)399-410
Number of pages12
JournalActa Chromatographica
Volume21
Issue number3
DOIs
Publication statusPublished - Sep 1 2009

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Rutin
Quercetin
Liver
Rats
Chamomile
Monitoring
Metabolism

Keywords

  • HPLC
  • Quercetin
  • Rat liver microsomes
  • Rutin
  • UV detection

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

HPLC monitoring of the microsomal stability of rutin and quercetin. / Szőke, E.; Petroianu, G.; Tekes, K.; Benko, B.; Szegi, P.; Laufer, R.; Veress, G.

In: Acta Chromatographica, Vol. 21, No. 3, 01.09.2009, p. 399-410.

Research output: Contribution to journalArticle

Szőke, E, Petroianu, G, Tekes, K, Benko, B, Szegi, P, Laufer, R & Veress, G 2009, 'HPLC monitoring of the microsomal stability of rutin and quercetin', Acta Chromatographica, vol. 21, no. 3, pp. 399-410. https://doi.org/10.1556/AChrom.21.2009.3.4
Szőke, E. ; Petroianu, G. ; Tekes, K. ; Benko, B. ; Szegi, P. ; Laufer, R. ; Veress, G. / HPLC monitoring of the microsomal stability of rutin and quercetin. In: Acta Chromatographica. 2009 ; Vol. 21, No. 3. pp. 399-410.
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