Gyogyszerkonyvi tisztasagvizsgalati feladatok megoldasa nagyhatekonysagu folyadekkromatografiaval

Translated title of the contribution: HPLC methods for compendial for purity tests

György Szász, Zsuzsa Budvári-Bárány, András Gergely, Krisztina Gyimesi-Forrás

Research output: Contribution to journalReview article

Abstract

The paper is addressed to the Institute of Pharmaceutical Chemistry, Budapest, on the 50th anniversary of its foundation, paying tribute to Prof. Antal Vegh, the first director of the Institute and his first deputy dr. Laszlo Auber and all the members of the Staff having merit in developing the research activity at the Department. After surveying the early papers published from the fifties through the seventies, concerning the profile of drug purity control, the factors increasing HPLC selectivity are shortly reviewed. In the concluding part of the paper, some recent results, as HPLC purity control methods suitable for compendial purposes (methylxanthines, opium alkaloids, tropane-alkaloids, enantiomer purity control of different drug compounds on glycoprotein and chirelcel columns) are summarized.

Translated title of the contributionHPLC methods for compendial for purity tests
Original languageHungarian
Pages (from-to)97-102
Number of pages6
JournalActa pharmaceutica Hungarica
Volume69
Issue number3
Publication statusPublished - Jun 1 1999

ASJC Scopus subject areas

  • Pharmaceutical Science

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